P
Peter Young
Researcher at University of Münster
Publications - 173
Citations - 11326
Peter Young is an academic researcher from University of Münster. The author has contributed to research in topics: Polysomnography & Hereditary neuralgic amyotrophy. The author has an hindex of 41, co-authored 166 publications receiving 10564 citations. Previous affiliations of Peter Young include École Polytechnique Fédérale de Lausanne & Medical Park.
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Journal ArticleDOI
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis.
Joseph C. Lee,Jeffrey T. Laydon,Peter C. McDonnell,Timothy Gallagher,Sanjay Kumar,David W. Green,Dean E. McNulty,M. J. Blumenthal,J. R. Heys,S. W. Landvatter,James E. Strickler,Megan M. McLaughlin,I. R. Siemens,Seth M. Fisher,George P. Livi,John R. White,Jerry L. Adams,Peter Young +17 more
TL;DR: Production of interleukin-1 and tumour necrosis factor from stimulated human monocytes is inhibited by a new series of pyridinyl-imidazole compounds, suggesting that the CSBPs are critical for cytokine production.
Journal ArticleDOI
Osteoprotegerin Is a Receptor for the Cytotoxic Ligand TRAIL
John Emery,Peter C. McDonnell,Michael Brigham Burke,Keith Charles Deen,Sally D. Lyn,Carol Silverman,Edward Dul,Appelbaum Edward Robert,Chris Eichman,Rocco DiPrinzio,R.A. Dodds,Ian E. James,Martin Rosenberg,John C. Lee,Peter Young +14 more
TL;DR: A fifth TRAIL receptor is identified, namely osteoprotegerin (OPG), a secreted tumor necrosis factor receptor homologue that inhibits osteoclastogenesis and increases bone density in vivo and is suggested to suggest potential cross-regulatory mechanisms by OPG and TRAIL.
Journal ArticleDOI
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: the PDGene database.
Christina M. Lill,Johannes T. Roehr,Johannes T. Roehr,Matthew B. McQueen,Fotini K. Kavvoura,Fotini K. Kavvoura,Fotini K. Kavvoura,Sachin Bagade,Brit-Maren M. Schjeide,Leif M. Schjeide,Esther Meissner,Ute Zauft,Nicole C. Allen,Tian-Jing Liu,Marcel Schilling,Marcel Schilling,Kari J. Anderson,Gary W. Beecham,Daniela Berg,Daniela Berg,Joanna M. Biernacka,Alexis Brice,Anita L. DeStefano,Chuong B. Do,Nicholas Eriksson,Stewart A. Factor,Matthew J. Farrer,Tatiana Foroud,Thomas Gasser,Thomas Gasser,Taye H. Hamza,John Hardy,Peter Heutink,Erin M. Hill-Burns,Christine Klein,Jeanne C. Latourelle,Demetrius M. Maraganore,Eden R. Martin,Maria Martinez,Maria Martinez,Richard H. Myers,Mike A. Nalls,Nathan Pankratz,Haydeh Payami,Wataru Satake,William K. Scott,Manu Sharma,Manu Sharma,Andrew B. Singleton,Kari Stefansson,Tatsushi Toda,Joyce Y. Tung,Jeffery M. Vance,Nicholas W. Wood,Cyrus P. Zabetian,Peter Young,Rudolph E. Tanzi,Muin J. Khoury,Frauke Zipp,Hans Lehrach,John P. A. Ioannidis,Lars Bertram,Lars Bertram +62 more
TL;DR: This study provides an exhaustive and up-to-date summary of the status of PD genetics research that can be readily scaled to include the results of future large-scale genetics projects, including next-generation sequencing studies.
Journal ArticleDOI
Role of csbp/p38/rk stress response kinase in lps and cytokine signaling mechanisms
John C. Lee,Peter Young +1 more
TL;DR: For the first time a definitive signal transduction pathway can be prescribed to the action of lipopolysaccharide in cytokine production in macrophages and CSAID™ cytokine biosynthesis inhibitors have been determined to be potent and selective inhibitors of CSBP/p38/RK kinase activity.
Journal ArticleDOI
Mutations in SEPT9 cause hereditary neuralgic amyotrophy.
Gregor Kuhlenbäumer,Gregor Kuhlenbäumer,Mark C. Hannibal,Eva Nelis,Anja Schirmacher,Nathalie Verpoorten,J. Meuleman,J. Meuleman,Giles D. J. Watts,Els De Vriendt,Peter Young,Florian Stögbauer,Hartmut Halfter,Joy Irobi,Dirk Goossens,Jurgen Del-Favero,Benjamin G Betz,Hyun Hor,Gert Kurlemann,Thomas D. Bird,Thomas D. Bird,Eila M. Airaksinen,Tarja Mononen,Adolfo Pou Serradell,José M Prats,Christine Van Broeckhoven,Peter De Jonghe,Vincent Timmerman,E. Bernd Ringelstein,Phillip F. Chance +29 more
TL;DR: Hereditary neuralgic amyotrophy is the first monogenetic disease caused by mutations in a gene of the septin family and three mutations in the gene septin 9 (SEPT9) in six families with HNA linked to chromosome 17q25 are reported.