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Pietro Ciancaglini
Researcher at Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto
Publications - 171
Citations - 3756
Pietro Ciancaglini is an academic researcher from Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto. The author has contributed to research in topics: Alkaline phosphatase & Vesicle. The author has an hindex of 30, co-authored 157 publications receiving 3206 citations. Previous affiliations of Pietro Ciancaglini include University of São Paulo & Federal University of São Carlos.
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Journal ArticleDOI
Biomedical applications of nanotechnology.
TL;DR: The chemical and physical properties of the surface of these materials allow their use in diagnosis, biosensing and bioimaging devices, drug delivery systems, and bone substitute implants, and toxicology of these particles is discussed in the light of a new field referred to as nanotoxicology that studies the surface effects emerging from nanostructured materials.
Journal ArticleDOI
Kinetic analysis of substrate utilization by native and TNAP-, NPP1-, or PHOSPHO1-deficient matrix vesicles.
Pietro Ciancaglini,Manisha C. Yadav,Ana Maria Simao,Sonoko Narisawa,João Martins Pizauro,Colin Farquharson,Marc Hoylaerts,Marc Hoylaerts,José Luis Millán +8 more
TL;DR: It is concluded that TNAP is the enzyme that hydrolyzes both ATP and PPi in the MV compartment, and NPP1 does not have a major role in PPi generation from ATP at the level of MVs, in contrast to its accepted role on the surface of the osteoblasts and chondrocytes.
Journal ArticleDOI
Use of hand held photopolymerizer to photoinactivate Streptococcus mutans.
Tony De Paiva Paulino,K.F. Ribeiro,Geraldo Thedei,Antonio Claudio Tedesco,Pietro Ciancaglini +4 more
TL;DR: The photoactivation of Rose Bengal, using the HHP, inactivated the bacteria without affecting the fibroblast viability and it was observed that the light is not toxic and in the dark Rose Bengal is toxic to the cells tested only at concentrations above 2.5 microM.
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Matrix vesicles from chondrocytes and osteoblasts: Their biogenesis, properties, functions and biomimetic models
Massimo Bottini,Saida Mebarek,Karen L. Anderson,Agnieszka Strzelecka-Kiliszek,Lukasz Bozycki,Ana Maria Simao,Maytê Bolean,Pietro Ciancaglini,Joanna Bandorowicz Pikula,Slawomir Pikula,David Magne,Niels Volkmann,Dorit Hanein,José Luis Millán,René Buchet +14 more
TL;DR: The prospects of employing upcoming experimental models to deepen the understanding of MV-mediated mineralization and mineralization disorders such as the use of reconstituted lipid vesicles, proteoliposomes and, native sample preparations and high-resolution technologies are discussed.
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Phosphodiesterase activity is a novel property of alkaline phosphatase from osseous plate.
TL;DR: The alkaline apparent pH optima, the requirement for bivalent metal ions and the inhibition by methylxanthines, amrinone and amiloride demonstrated that rat osseous-plate alkaline phosphatase was a type I phosphodiesterase.