P
Punith Kempegowda
Researcher at University of Birmingham
Publications - 85
Citations - 723
Punith Kempegowda is an academic researcher from University of Birmingham. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 8, co-authored 39 publications receiving 501 citations. Previous affiliations of Punith Kempegowda include University Hospitals Birmingham NHS Foundation Trust & University of Buckingham.
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Journal ArticleDOI
11-oxygenated C19 steroids are the predominant androgens in polycystic ovary syndrome.
Michael W O'Reilly,Michael W O'Reilly,Punith Kempegowda,Punith Kempegowda,Carl Jenkinson,Carl Jenkinson,Angela E Taylor,Angela E Taylor,Jonathan L. Quanson,Karl-Heinz Storbeck,Wiebke Arlt,Wiebke Arlt,Wiebke Arlt +12 more
TL;DR: It is shown that 11-oxygenated androgens represent the majority of circulating androgens in women with PCOS, with close correlation to markers of metabolic risk and markers of insulin resistance.
Journal ArticleDOI
AKR1C3-Mediated Adipose Androgen Generation Drives Lipotoxicity in Women With Polycystic Ovary Syndrome
Michael W O'Reilly,Michael W O'Reilly,Punith Kempegowda,Punith Kempegowda,Mark D. Walsh,Angela E Taylor,Angela E Taylor,Konstantinos N. Manolopoulos,Konstantinos N. Manolopoulos,J. William Allwood,Robert K. Semple,Daniel Hebenstreit,Warwick B. Dunn,Jeremy W. Tomlinson,Wiebke Arlt,Wiebke Arlt +15 more
TL;DR: An intra‐adipose mechanism of androgen activation that contributes to adipose remodeling and a systemic lipotoxic metabolome is defined, with intra‐ adipose androgens driving lipid accumulation and insulin resistance in PCOS.
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Clinico-microbiological profile of urinary tract infection in south India.
TL;DR: A high rate of ESBL-positive organisms and their resistance to commonly used antibiotics brings a concern for future options in treating these conditions.
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MECHANISMS IN ENDOCRINOLOGY: The sexually dimorphic role of androgens in human metabolic disease
TL;DR: It is hypothesised that serum androgen concentrations observed in female androgen excess and male hypogonadism are metabolically disadvantageous, promoting adipose and liver lipid accumulation, central fat mass expansion and insulin resistance.
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Significance of serum procalcitonin in sepsis.
TL;DR: Procalcitonin (PCT) proved to be an excellent indicator of sepsis with sensitivity of 94% and there was a significant association between serum PCT and SOFA scores (P < 0.05).