R
R. Beresford
Researcher at University of Otago
Publications - 4
Citations - 1253
R. Beresford is an academic researcher from University of Otago. The author has contributed to research in topics: Molecular descriptor & Nonlinear system. The author has an hindex of 4, co-authored 4 publications receiving 919 citations.
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Basic concepts of artificial neural network (ANN) modeling and its application in pharmaceutical research
TL;DR: Artificial neural networks are biologically inspired computer programs designed to simulate the way in which the human brain processes information and represent a promising modeling technique, especially for data sets having non-linear relationships which are frequently encountered in pharmaceutical processes.
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Theoretically-derived molecular descriptors important in human intestinal absorption.
TL;DR: Results obtained indicate that lipophilicity, conformational stability and inter-molecular interactions (polarity, and hydrogen bonding) have the largest impact on intestinal absorption.
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ANN modeling of the penetration across a polydimethylsiloxane membrane from theoretically derived molecular descriptors.
TL;DR: Model indicates that molecular shape and size, inter-molecular interactions, hydrogen-bonding capacity of drugs, and conformational stability could be used to predict drug absorption through skin and could potentially provide useful prediction of membrane penetration of new drugs.
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Determination of enantiomeric composition of ibuprofen in solid state mixtures of the two by DRIFT spectroscopy
TL;DR: In this paper, the enantiomeric purity of ibuprofen was determined by diffuse reflectance infrared Fourier transform (DRIFT) spectroscopy with artificial neural networks (ANNs) methodology.