R
Raymond Chermat
Researcher at French Institute of Health and Medical Research
Publications - 32
Citations - 4326
Raymond Chermat is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Diazepam & Apomorphine. The author has an hindex of 18, co-authored 32 publications receiving 4025 citations.
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The tail suspension test: A new method for screening antidepressants in mice
TL;DR: A novel test procedure for antidepressants was designed in which a mouse is suspended by the tail from a lever, the movements of the animal being recorded, and the test can separate the locomotor stimulant doses from antidepressant doses.
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The automated tail suspension test: A computerized device which differentiates psychotropic drugs
Lucien Steru,Raymond Chermat,Bernard Thierry,Juan-Antonio Mico,Antoine Lenègre,Marius Steru,Pierre Simon,Roger D. Porsolt +7 more
TL;DR: A computerized version of this test (ITEMATIC-TST) which in addition to recording immobility measures the power of the movements, suggesting that the automated test system is not only sensitive to antidepressants but could also be useful for generating activity profiles for different kinds of psychotropic agent.
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A simple model for studying benzodiazepines: Potentiation of hyperactivity induced by cocaine in mice
Marie-Hélène Thiébot,Joseph Kloczko,Raymond Chermat,Philippe Soubrie,Alain J. Puech,Pierre Simon +5 more
TL;DR: The results suggest that benzodiazepines may exert their facilitatory activity on cocaine‐induced hyperactivity by interfering with some central catecholaminergic processes either directly or through the involvement of a GABA‐ergic link.
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Searching-Waiting Strategy: A Candidate for an Evolutionary Model of Depression?
TL;DR: The model proposed here assumes that depressive disorders could reflect an extreme state of a current behavioral strategy, namely, infant response to maternal separation in monkeys and "behavioral despair" in rodents.
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Synthèses et activités psychotropes de 3,4-diarylpipéridines. Corrélation structure-activité et recherche d'une activité antihypertensive
S Petit,JP Nallet,M Guillard,J. Dreux,Raymond Chermat,M. Poncelet,C Bulach,Pierre Simon,C Fontaine,Mariette Barthelmebs,Jean-Louis Imbs +10 more
TL;DR: In this paper, a series of 3,4-diarylpiperidines (3-phenyl piperidine) were investigated for psychotropic properties (psychostimulant, anti-depressant) using Topliss method.