R
Richard A. J. O'Hair
Researcher at University of Melbourne
Publications - 403
Citations - 10890
Richard A. J. O'Hair is an academic researcher from University of Melbourne. The author has contributed to research in topics: Dissociation (chemistry) & Mass spectrometry. The author has an hindex of 48, co-authored 391 publications receiving 10150 citations. Previous affiliations of Richard A. J. O'Hair include Walter and Eliza Hall Institute of Medical Research & La Trobe University.
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Journal ArticleDOI
MR1 presents microbial vitamin B metabolites to MAIT cells
Lars Kjer-Nielsen,Onisha Patel,Alexandra J. Corbett,Jérôme Le Nours,Jérôme Le Nours,Bronwyn S. Meehan,Ligong Liu,Mugdha Bhati,Zhenjun Chen,Lyudmila Kostenko,Rangsima Reantragoon,Nicholas A. Williamson,Anthony W. Purcell,Anthony W. Purcell,Nadine L. Dudek,Nadine L. Dudek,Malcolm J. McConville,Richard A. J. O'Hair,George N. Khairallah,Dale I. Godfrey,David P. Fairlie,Jamie Rossjohn,Jamie Rossjohn,Jamie Rossjohn,James McCluskey +24 more
TL;DR: It is shown that metabolites of vitamin B represent a class of antigen that are presented by MR1 for MAIT-cell immunosurveillance, and data suggest that MAIT cells use these metabolites to detect microbial infection.
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Mining a tandem mass spectrometry database to determine the trends and global factors influencing peptide fragmentation.
Eugene A. Kapp,Frédéric Schütz,Gavin E. Reid,James S. Eddes,Robert L. Moritz,Richard A. J. O'Hair,Terence P. Speed,Richard J. Simpson +7 more
TL;DR: A database of 5500 unique peptide tandem mass spectra acquired in an ion trap mass spectrometer was assembled for peptides derived from proteins digested with trypsin to derive a new classification scheme, the "relative proton mobility" scale, which considers peptide ion charge state and amino acid composition to categorize peptides into peptide ions containing "nonmobile", "partially mobile", or "mobile" protons.
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The 3D quadrupole ion trap mass spectrometer as a complete chemical laboratory for fundamental gas-phase studies of metal mediated chemistry
TL;DR: Electrospray ionization provides a "treasure trove" of metal containing ions whose fundamental reactivity can be studied via collision induced dissociation and ion-molecule reactions using the multistage mass Spectrometry capabilities of the quadrupole ion trap mass spectrometer.
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Catalytic Gas Phase Oxidation of Methanol to Formaldehyde
TL;DR: Three reactions of these cycles are equivalent to the three essential steps proposed to occur in the industrial oxidation of gaseous methanol to formaldehyde at 300-400 degrees C over solid-state catalysts based upon molybdenum(VI)-trioxide.