R
Roberto Bolli
Researcher at University of Louisville
Publications - 543
Citations - 45789
Roberto Bolli is an academic researcher from University of Louisville. The author has contributed to research in topics: Myocardial infarction & Ischemic preconditioning. The author has an hindex of 111, co-authored 528 publications receiving 44010 citations. Previous affiliations of Roberto Bolli include Guy's and St Thomas' NHS Foundation Trust & New York Medical College.
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Journal ArticleDOI
Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial.
Roberto Bolli,Atul R. Chugh,Domenico D'Amario,John H Loughran,Marcus F. Stoddard,Sohail Ikram,Garth M. Beache,Stephen G. Wagner,Annarosa Leri,Toru Hosoda,Fumihiro Sanada,Julius B Elmore,Polina Goichberg,Donato Cappetta,Naresh K Solankhi,Ibrahim Fahsah,D. Gregg Rokosh,Mark S. Slaughter,Jan Kajstura,Piero Anversa +19 more
TL;DR: It is suggested that intracoronary infusion of autologous CSCs is effective in improving LV systolic function and reducing infarct size in patients with heart failure after myocardial infarction, and warrant further, larger, phase 2 studies.
Journal ArticleDOI
Molecular and Cellular Mechanisms of Myocardial Stunning
Roberto Bolli,Eduardo Marbán +1 more
TL;DR: An important implication of the phenomenon of myocardial stunning is that so-called chronic hibernation may in fact be the result of repetitive episodes of stunning, which have a cumulative effect and cause protracted postischemic dysfunction.
Journal ArticleDOI
Human cardiac stem cells
Claudia Bearzi,Marcello Rota,Toru Hosoda,Jochen Tillmanns,Angelo Nascimbene,Antonella De Angelis,Saori Yasuzawa-Amano,Irina Trofimova,Robert W. Siggins,Nicole LeCapitaine,Stefano Cascapera,Antonio Paolo Beltrami,David A. D'Alessandro,Elias Zias,Federico Quaini,Konrad Urbanek,Robert E. Michler,Roberto Bolli,Jan Kajstura,Annarosa Leri,Piero Anversa +20 more
TL;DR: The identification in vitro of a class of human c-kit-positive cardiac cells that possess the fundamental properties of stem cells: they are self-renewing, clonogenic, and multipotent is reported.
Journal ArticleDOI
Mechanism of myocardial "stunning".
TL;DR: The concepts discussed in this review should provide not only a conceptual framework for further investigation of the pathophysiology of reversible ischemia-reperfusion injury but also a rationale for developing clinically applicable interventions designed to prevent postischemic ventricular dysfunction.
Journal ArticleDOI
Adult bone marrow-derived cells for cardiac repair: a systematic review and meta-analysis.
Ahmed Abdel-Latif,Roberto Bolli,Imad M. Tleyjeh,Victor M. Montori,Emerson C. Perin,Carlton A. Hornung,Ewa K. Zuba-Surma,Mouaz H. Al-Mallah,Buddhadeb Dawn +8 more
TL;DR: The available evidence suggests that BMC transplantation is associated with modest improvements in physiologic and anatomic parameters in patients with both acute myocardial infarction and chronic ischemic heart disease, above and beyond conventional therapy.