Sandra Downes

TL;DR: Poor biocompatibility and induction of apoptosis on collagen/poly(vinyl alcohol) films crosslinked by glutaraldehyde are attributed to glutaralde components on the surface of the films (not residual glutarhyde), whose effects can be quenched by glutamic acid, and prevented by insulin-like growth factor-1.

TL;DR: Electrospinning of the elastomer PLGA produced aligned fibres that had the correct topology to provide contact guidance for myoblast elongation and alignment and required no surface modifications or incorporation of biologic material for adhesion, elongation, and differentiation of C2C12 murine myoblasts.

TL;DR: In this paper, the C 1 s, N 1 s and O 1 s core level binding energies (BEs) of the functional groups in amino acids (glycine, aspartic acid, glutamic acid, arginine, and histidine) with varied side-chains and cell-binding RGD-based peptides have been determined and characterized by X-ray photoelectron spectroscopy with a monochromatic Al Kα source.

TL;DR: Protein adsorption and growth of primary human osteoblasts on self-assembled monolayers of alkylthiols on gold (SAMs) with carboxylic acid and hydroxyl and methyl termini were investigated and cell growth on patterned SAMs demonstrated preferences for one pattern region in all combinations of alkies.

TL;DR: Cell incorporation into conduit repair of peripheral nerves demonstrates experimental promise as a novel intervention to prevent DRG neuronal loss.