S
Sarah L. Waters
Researcher at University of Oxford
Publications - 168
Citations - 3744
Sarah L. Waters is an academic researcher from University of Oxford. The author has contributed to research in topics: Reynolds number & Population. The author has an hindex of 32, co-authored 163 publications receiving 3288 citations. Previous affiliations of Sarah L. Waters include Northwestern University & University of Nottingham.
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Journal ArticleDOI
Mechanics of the brain: perspectives, challenges, and opportunities
Alain Goriely,Mgd Marc Geers,Gerhard Holzapfel,Jayaratnam Jayamohan,Antoine Jérusalem,Sivabal Sivaloganathan,W Waney Squier,Jaw Hans van Dommelen,Sarah L. Waters,Ellen Kuhl +9 more
TL;DR: It is shown that classical mechanical concepts including deformations, stretch, strain, strain rate, pressure, and stress play a crucial role in modulating both brain form and brain function.
Journal ArticleDOI
Chaste: A test-driven approach to software development for biological modelling☆
Joe Pitt-Francis,Pras Pathmanathan,Miguel O. Bernabeu,Rafel Bordas,Jonathan Cooper,Alexander G. Fletcher,Gary R. Mirams,Philip J. Murray,James M. Osborne,Alex Walter,S. Jonathan Chapman,Alan Garny,Ingeborg M.M. van Leeuwen,Philip K. Maini,Blanca Rodriguez,Sarah L. Waters,Jonathan P. Whiteley,Helen M. Byrne,David J. Gavaghan +18 more
TL;DR: Chaste (‘Cancer, heart and soft-tissue environment’) is a software library and a set of test suites for computational simulations in the domain of biology and has been developed using agile programming methods.
Journal ArticleDOI
An integrative computational model for intestinal tissue renewal
I.M.M. van Leeuwen,I.M.M. van Leeuwen,Gary R. Mirams,A. Walter,Alexander G. Fletcher,Philip J. Murray,James M. Osborne,Susheel Varma,Sarah Young,Jonathan Cooper,Barney Lee Doyle,Joe Pitt-Francis,Lee Momtahan,Pras Pathmanathan,Jonathan P. Whiteley,Stephen J Chapman,David J. Gavaghan,Oliver E. Jensen,John R. King,Philip K. Maini,Sarah L. Waters,Helen M. Byrne +21 more
TL;DR: A new multiscale model for crypt dynamics is proposed that links phenomena occurring at the subcellular, cellular and tissue levels of organisation to investigate how its dysfunction can lead to loss of homeostasis and neoplasia.
Journal ArticleDOI
Homogenization via formal multiscale asymptotics and volume averaging: How do the two techniques compare?
Yohan Davit,Yohan Davit,Christopher G. Bell,Helen M. Byrne,Lloyd A. C. Chapman,L. S. Kimpton,Georgina E. Lang,Katherine H.L. Leonard,James M. Oliver,Natalie Pearson,Rebecca J. Shipley,Sarah L. Waters,Jonathan P. Whiteley,Brian D. Wood,Michel Quintard,Michel Quintard +15 more
TL;DR: The goal is to bridge the gap between formal multiscale asymptotics and the volume averaging theory and, in so doing, compare their respective advantages/disadvantages from a practical point of view.
Journal ArticleDOI
The EuroPhysiome, STEP and a roadmap for the virtual physiological human
John Fenner,Bindi S. Brook,Gordon Clapworthy,Peter V. Coveney,Véronique Feipel,Hans Gregersen,D. R. Hose,Peter Kohl,Patricia V. Lawford,Keith McCormack,D. Pinney,S. R. Thomas,S. Van Sint Jan,Sarah L. Waters,Marco Viceconti +14 more
TL;DR: This paper considers issues pertinent to the development of the VPH, highlighted by the work of the STEP consortium, to create a framework capable of describing Homo sapiens in silico.