Satoshi Kimura

TL;DR: Never-Dried and once-dried hardwood celluloses were oxidized by a 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO)-mediated system, and highly crystalline and individualized cellulose nanofibers, dispersed in water, were prepared by mechanical treatment of the oxidized celluloses/water slurries.

TL;DR: This study provides the first direct evidence that adiponectin plays a protective role against insulin resistance and atherosclerosis in vivo.

TL;DR: It is demonstrated that simple SDS-PAGE under non-reducing and non-heat-denaturing conditions clearly separates multimer species of adiponectin.

TL;DR: It is shown that replenishment of globular adiponectin may provide a novel treatment modality for both type 2 diabetes and atherosclerosis, and this is the first demonstration that globular leptin can protect against Atherosclerosis in vivo.

TL;DR: The ability of insulin to lower the plasma glucose level in the HCV transgenic mice was impaired, as observed in chronic hepatitis C patients, providing a direct experimental evidence for the contribution of HCV in the development of insulin resistance in human HCV infection, which finally leads to theDevelopment of type 2 diabetes.