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Sharon L.R. Kardia

Researcher at University of Michigan

Publications -  519
Citations -  43104

Sharon L.R. Kardia is an academic researcher from University of Michigan. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 90, co-authored 454 publications receiving 34842 citations. Previous affiliations of Sharon L.R. Kardia include Pennington Biomedical Research Center & University of California, San Diego.

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Gene-expression profiles predict survival of patients with lung adenocarcinoma

TL;DR: The identification of a set of genes that predict survival in early-stage lung adenocarcinoma allows delineation of a high-risk group that may benefit from adjuvant therapy.
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Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Georg Ehret, +391 more
- 06 Oct 2011 - 
TL;DR: A genetic risk score based on 29 genome-wide significant variants was associated with hypertension, left ventricular wall thickness, stroke and coronary artery disease, but not kidney disease or kidney function, and these findings suggest potential novel therapeutic pathways for cardiovascular disease prevention.
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Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries

Mary F. Feitosa, +299 more
- 18 Jun 2018 - 
TL;DR: In insights into the role of alcohol consumption in the genetic architecture of hypertension, a large two-stage investigation incorporating joint testing of main genetic effects and single nucleotide variant (SNV)-alcohol consumption interactions is conducted.
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Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps.

Anubha Mahajan, +131 more
- 08 Oct 2018 - 
TL;DR: Combining 32 genome-wide association studies with high-density imputation provides a comprehensive view of the genetic contribution to type 2 diabetes in individuals of European ancestry with respect to locus discovery, causal-variant resolution, and mechanistic insight.
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Genome-wide association study identifies 74 loci associated with educational attainment

Aysu Okbay, +296 more
- 26 May 2016 - 
TL;DR: In this article, the results of a genome-wide association study (GWAS) for educational attainment were reported, showing that single-nucleotide polymorphisms associated with educational attainment disproportionately occur in genomic regions regulating gene expression in the fetal brain.