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Simon Carley
Researcher at Manchester Metropolitan University
Publications - 168
Citations - 4906
Simon Carley is an academic researcher from Manchester Metropolitan University. The author has contributed to research in topics: Emergency department & Myocardial infarction. The author has an hindex of 31, co-authored 162 publications receiving 3986 citations. Previous affiliations of Simon Carley include National Health Service & Central Manchester University Hospitals NHS Foundation Trust.
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Journal ArticleDOI
Lopinavir–ritonavir in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
Peter Horby,M Mafham,Jennifer L Bell,Louise Linsell,Natalie Staplin,Jonathan Emberson,Adrian Palfreeman,Jason Raw,E Elmahi,B Prudon,Christopher A Green,Simon Carley,David Chadwick,Matthew N. Davies,Matt P. Wise,J Kenneth Baillie,Lucy C Chappell,Saul N. Faust,Thomas Jaki,Katie Jefferey,Wei Shen Lim,Alan A Montgomery,Kathryn M Rowan,Edmund Juszczak,Richard Haynes,Martin J Landray +25 more
TL;DR: In patients admitted to hospital with COVID-19, lopinavir–ritonavir was not associated with reductions in 28-day mortality, duration of hospital stay, or risk of progressing to invasive mechanical ventilation or death.
Journal ArticleDOI
An introduction to power and sample size estimation
TL;DR: The importance of power and sample size estimation for study design and analysis and the role of meta-analysis in this work is illustrated.
Journal ArticleDOI
Rapid exclusion of acute myocardial infarction in patients with undetectable troponin using a high-sensitivity assay.
Richard Body,Simon Carley,Garry McDowell,Allan S. Jaffe,Kennedy Cruickshank,Christopher Wibberley,Michelle Nuttall,Kevin Mackway-Jones +7 more
TL;DR: Undetectable hs-cTnT at presentation has very high negative predictive value, which may be considered to rule out AMI, identifying patients at low risk of adverse events and reducing the need for serial testing and empirical treatment.
Journal ArticleDOI
Serious gaming technology in major incident triage training: A pragmatic controlled trial ☆
James F. Knight,Simon Carley,Bryan Tregunna,Steve Jarvis,Richard Smithies,Sara de Freitas,Ian Dunwell,Kevin Mackway-Jones +7 more
TL;DR: Evaluating the effectiveness of a serious game in the teaching of major incident triage by comparing it with traditional training methods found it to offer the potential to enhance learning and improve subsequent performance when compared to traditional educational methods.
Journal ArticleDOI
Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial
Ian Roberts,Haleema Shakur-Still,AO Afolabi,Adegboyega Akere,Monica Arribas,Amy Brenner,Rizwana Chaudhri,Ian Gilmore,Kenneth Halligan,Irshad Hussain,Vipul Jairath,Kiran Javaid,Aasia Kayani,Ton Lisman,Raoul Mansukhani,Muttiullah Mutti,Muhammad Nadeem,Richard Pollok,Jonathan Simmons,Majid Soomro,Simon J. Stanworth,Andrew Veitch,Christopher J. Hawkey,Jack Cuzick,David Henry,Chris Metcalfe,Richard Gray,Alan N. Barkun,Suresh David,Philip J. Devereaux,Tony Brady,Timothy J Coats,Phil Edwards,Katharine Ker,Daniela Manno,Emma Austin,Kiran Bal,Eni Balogun,Collette Barrow,Danielle Beaumont,Myriam Benyahia,Imogen Brooks,Madeleine Cargill,Laura Carrington,Lauren Frimley,Amber Geer,Daniel Gilbert,Catherine Gilliam,Julio Onandia,Nayia Golfi,Daniel Hetherington,Courtenay Howe,Carolyn Hughes,David I'Anson,Robert B. Jackson,Miland Joshi,Sneha Kansagra,T Kawahara,Sergey Kostrov,Hakim Miah,Bernard Ndungu,Kelly Needham,Aroudra Outtandy,Daniel Pearson,Tracey Pepple,Danielle Prowse,Nigel Quashi,Anna Quinn,M Ramos,Laura Ranopa,Mia Reid,Chris Roukas,Chelci Squires,Jemma Tanner,Andrew Thayne,Ruhama Uddin,Bukola Fawole,Folasade Adenike Bello,Oladapo Olayemi,Olujide Okunade,Olusade Adetayo,Hussein Khamis,Mohammad Shukri Bin Jahit,Tamar Gogichaishvili,Radu Bogdan Mateescu,Ajay Adhikaree,Abdelmounem Eltayeib Abdo,Mohammad Zaher,Conor Deasy,Joaquin Alvarez Gregori,Bobby Wellsh,Luke Lawton,Raghavendra Kamath,Adrian Barry,Racquel Carpio,Kay Finney,Holly Maguire,Martin James,Frank Coffey,Christopher. Gough,Lisa Sawers,Aye-Aye Thi,Claire Burnett,Nicola Jacques,Victoria Murray,Heather Jarman,Christine Lambe,Sarah. Rounding,Simon Tucker,Romaih Al-Idari,Samuel Guest,Emma Stoddard,David Yeo,Colin Bergin,Elaine Hardy,Joanne Thunder,Paul Jhalli,Edward Hartley,Catherine Jarvis,Carly Swann,Matthew J. Reed,Bernadette Gallagher,Julia Grahamslaw,Rachel O’Brien,Tim Harris,Geoffrey Bellhouse,Olivia Boulton,Imogen Skene,Adrian J. Stanley,Janet Johnstone,Donogh Maguire,Susan Thornton,Matthew Banks,Georgia Bercades,Daniel Marks,Jung Ryu,Claire Dowty,Jason Pott,James East,Adam A. Bailey,Sally Beer,Sian Davies,Andrew Appelboam,Daisy. Mackle,Jennifer Small,Christiane Vorwerk,Rachel Atkins,Isobel Bradbury,Catriona Bryceland,Lisa McClelland,Martin Thomas,Kate Clayton,Angiy Michael,Stephen Haig,Saif Al-Nahhas,Tim Godfrey,Philip Boger,Rachel Comer,Barbara Watkins,Ola Afolabi,Shazad Afzal,Amanda Cowton,Simon M Everett,Ruth Fazakerley,Felicia Onoviran,Jonathon Snook,Jackie Berry,Diane Simpson,Jeff Keep,Hannah. Cotton,Sinead Helyar,Matthew Rutter,Tracey Johnston,Laura O'Rourke,Louisa Chan,Joanna Tambellini,Dawn Trodd,James Shutt,Sarah Moreton,Abby Oglesby,Adrian Boyle,Nicola Haeger,Susie Hardwick,Jason Kendall,Beverley Faulkner,Ruth Worner,Sarah Hearnshaw,Mary Doona,Maria Price,Laura Hunter,Maggie Bell,Vania Loureiro,Anthony Kehoe,Alison Jefferey,Rosalyn Squire,David Hartin,Stephanie Bell,Alexandra Newman,James Gagg,Jayne Foot,Sue Wakeford,Gabrielle May,Thomas Bartram,Paul Cumpstay,Lucy Parker,Rita Das,Sheik Pahary,Gavin J. Wright,Georgina Butt,Natasha Christmas,Sarah L Wilson,Mohammed Ashfaq,Louise Chandler,Carrie Demetriou,Philip Kaye,Simon Carley,Andrew Brown,Lucy H. Jones,Amanda Whileman,J Greenaway,Julie Tregonning,Avril Kuhrt,Steve Goodacre,John Jones,Charlotte Owen,Anu Mitra,Abby Harper-Payne,Nigel Trudgill,Anne Hayes,Faheem Butt,Gayle Clifford,Andrew Kinnon,Susan Fowler,Kris Pillay,Shweta Gidwani,Alistair McNair,Omer Omer,Tanya de Weymarn,Adnan Amin,Jane Martin,Nick Mathieu,Simon Barnes,James Turvill,Helen Sweeting,Morten Draegebo,Marion McNaught,Mandy Grocutt,Jordi Margalef,Julian Humphrey,Richard J. Jackson,Fionn Bellis,Jane Hunt,Alastair Stevenson,Nick Watson,Steven Barden,Stuart Paterson,Chris Macdonald,David Hobday,Olu Orugun,Andrew Allison,Tristan Dyer,Samuel McBride,Wojciech Sawicki,Ben Rayner,Lynsey Flowerdew,Jamie Barbour,Jason Klein,Stephen Hood,Nicola Palmer,Jacob de Wolff,Achuth Shenoy,Peter Swallow,Rajaventhan Srirajaskanthan,Hamza Arshad,Naeem Aslam,Anam Bangash,Muhammad Qamar,Haroon Zahoor,Saba Arshad,Quratul ain Ghalib,Tehseen Hameed,Tayyaba Saif,Wajahat Shafi,Abid Ali,Shehroze Khan,Muhammad Muaaz,Ahmad Taj,Aamir Ghafoor,Aamir Afridi,Mansoor Ahmad,Mujahid Aslam,Sandeep Kumar,Mohsin Ali,Ubedullah Bughio,Adil Chang,Sana Shaikh,Syed F Ahmad,Zeeshan Ali,Marium Waqar,Aiman Mushir,Sadaf Sattar,Saifullah Goraya,Sharmeen Aslam,Nighat Fatima,Saadia Noreen,Sheraz Saleem,Fazal Rahman,Nadeem Iqbal,Mohammad Khalid,Umar Riaz,Muhammad Umar,Tayyab Akhter,Javaria Khan,Noureen Misbah,Muhammad Shuaib Afzal,Mobeen Kayani,Syed Ahmar Shah,Shahida Tarar,Sherbat Khan,Yasir Iqbal,Essa Khan,Maqbool Reki,Tanveer Hussain,Shafqat Iqbal,Muhammad Khurram,Muhammad Shafi,Abrar Shaikh,Aijaz Ahmed,Ameet Kumar,Pinkey Sachdev,Khalid Mahmood Nasir,Zafar Iqbal Chaudhry,Muhammad Zubair,Ghias Tayyab,Junaid Mushtaq,Muhammad Nasir,Akram Khan,Amjad Ali,Sajjad Ali,Wasim Uddin,Sohaib Ahmed,Tazaeen Kazmi,Saleh Channa,Adeeqa Aman,Mouzam Shaikh,Tahir Rizvi,Amjad Hussain,Haider Zaigham Baqai,Zakawat Rasheed,Abdus Salam Khan,Adeela Irfan,Aamir Husain,Asifa Aslam,Khalid Yahya,Salman Azhar,Mansoor Ul Haq,Adeel Afzal,Muhammad Imran,Iram Saeed,Aasim Yusuf,Mariam Hassan,Mumtaz Marwat,Muhammad Ishfaq,Tahir Bashir,Santosh Kumar,Sajjad Yaqoob,Abdul Wahid,Tinuola Fakoya,Temitope Oke,Edries Tejan,Oluwole Olaomi,Olawale Badejo,Okafor Nnaemaka,Nancy Ukwu,Olukayode Arowolo,Adewale Aderounmu,Funmilola Wuraola,Rose Ugiagbe,Alexander Atiri,Enadeghe Eghaghe,Adeleke Adekoya,Adedayo Oluyomi Tade,Olatunji Shonoiki,Samuel Olatoke,Toafiq Raji,Christopher Ekwunife,Chigozirim Onyekpere,Adamu Ahmed,Daniyan Muhammad,Emuobor Odeghe,Olufunmilayo Lesi,Azeberoje Osueni,Adamu Samaila,Aminu Nahuche,Akande Ajayi,Andrew Dongo,Uchenna Ijoma,Ademola Tolulope Adebanjo,Rufina Igetei,Monday Yilkudi,Kehinde Osisanya,Edith Nonyelum Okeke,Oguamanam Okezie Enwere,Serag Esmat,Omar Ashoush,Mazen Naga,Fady Nagy,Mostafa Saiid,Ahmed Shaker,Ashraf Helmy,Saafan Saafan,Mohammed Abdel Monem,Jiffre Din,Khairul Azis,Muhyuddin Brukan,Sanjay Singh,Andee Dzulkarnaen Zakaria,Shaik Farid,Nizam Hashim,Masykurin Mafauzy,Wan Najmi,Nil Amri,Xin Yi,Mohammad Hisyam,Elaine Ng,Zuhrirahimi Ramli,Shyang Yee Lim,Kelvin Voon,Sir Young Yam,Mohammad Jahit,Lee Joon,Besik Melikidze,Davit Kazaishvili,Nino Grubelashvili,Baadur Mosidze,Gia Tomadze,Avto Megreladze,Ruxandra Oprita,Dorina Pestroiu Calescu,Camelia Chioncel,Andrei Ragea,Bogdan Mateescu,Bogdan Busuioc,Andrei Voiosu,Adrian Cotirlet,Iulia Pintilie,Mariana Jinga,Daniel Vasile Balaban,Marcel Tanău,Lucian Negreanu,Simona Bataga,Khushboo Priya,Shankar Baral,K C Anuj,Vijay Sah,Vijay K. Yadav,Abdelmounem Abdo,Dalia Ahmed,Marzouqah Al Anazi,Areej Al Balkhi,Helio Fornieles Pérez,Arben Beqiri +461 more
TL;DR: It was found that tranexamic acid did not reduce death from gastrointestinal bleeding and should not be used for the treatment of gastrointestinal bleeding outside the context of a randomised trial.