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Slobodan Rendic
Researcher at University of Zagreb
Publications - 27
Citations - 3221
Slobodan Rendic is an academic researcher from University of Zagreb. The author has contributed to research in topics: Cytochrome P450 & Drug metabolism. The author has an hindex of 15, co-authored 26 publications receiving 2972 citations.
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Human Cytochrome P450 Enzymes: A Status Report Summarizing Their Reactions, Substrates, Inducers, and Inhibitors
TL;DR: A status report summarizing their reactions, substrates, Inducers, and Inhibitors is given in this article, with a focus on human CYtochrome P450 enzymes.
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Summary of information on human cyp enzymes: human p450 metabolism data
TL;DR: This chapter is an update of the data on substrates, reactions, inducers, and inhibitors of human CYP enzymes published previously by Rendic and DiCarlo, now covering selection of the literature through 2001 in the reference section.
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Survey of Human Oxidoreductases and Cytochrome P450 Enzymes Involved in the Metabolism of Xenobiotic and Natural Chemicals.
TL;DR: The calculations show that the fractions of P450s involved in the metabolism of all chemicals (general chemicals, natural, and physiological compounds, and drugs) are rather consistent in the findings that >90% of enzymatic reactions are catalyzed by P 450s.
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Contributions of human enzymes in carcinogen metabolism.
TL;DR: The metabolism and especially bioactivation of carcinogens are dominated by cytochrome P450 enzymes, which can be compared with those estimated for drug metabolism and should be considered in issues involving enzyme induction, chemoprevention, molecular epidemiology, interindividual variations, and risk assessment.
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Interaction of Cimetidine with Liver Microsomes
TL;DR: The O-dealkylation of 7-ethoxycoumarin and of p-nitroanisole was inhibited by the presence of ranitidine and the inhibition was of a mixed type.