Stefan K. Nilsson

TL;DR: The messenger RNA expression of both ER subtypes in rat tissues by RT-PCR is investigated and the ligand binding specificity of the ER sub types is compared, revealing a single binding component for 16β-estradiol with high affinity.

TL;DR: In this article, a cell comprising an estrogen receptor beta (ER beta ), AP1 proteins, and a construct comprising a promoter comprising an AP1 site which regulates expression of a first reporter gene is contacted with the test compound and changes in expression levels of the reporter gene are detected indicating whether the test compounds activate transcription, inactivate transcription or have no effect at the AP1 sites.

TL;DR: Findings suggest that ligands specific for ERβ may be useful in the prevention and/or clinical management of prostatic hyperplasia and neoplasia.

TL;DR: In this article, the authors support the use of regulatory T cells (Tregs) as inhibitors of atherosclerosis, however, the mechanistic properties of Tregs are unknown.

TL;DR: It is demonstrated that FOXP3(+) Tregs inhibit atherosclerosis by modulating lipoprotein metabolism by mediating the altered lipid phenotype.