S
Stephen J. Roth
Researcher at Stanford University
Publications - 94
Citations - 6038
Stephen J. Roth is an academic researcher from Stanford University. The author has contributed to research in topics: Intensive care & Extracorporeal membrane oxygenation. The author has an hindex of 32, co-authored 91 publications receiving 5646 citations. Previous affiliations of Stephen J. Roth include Boston Children's Hospital & Johns Hopkins University.
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Journal ArticleDOI
Monocyte chemoattractant protein 1 acts as a T-lymphocyte chemoattractant
TL;DR: MCP-1 is the major lymphocyte chemoattractant secreted by mitogen-stimulated peripheral blood mononuclear cells and is capable of acting as a potent T-lymphocyte, as well as monocyte, chemoATTractant.
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Neutrophil rolling, arrest, and transmigration across activated, surface-adherent platelets via sequential action of P-selectin and the beta 2-integrin CD11b/CD18.
TL;DR: It is demonstrated that the beta 2-integrin Mac-1 (CD11b/CD18) is required for both firm attachment to and transmigration of neutrophils across surface-adherent platelets and may play an important role in promoting neutrophil accumulation on and migration across platelets deposited at sites of vascular injury.
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Effect of a Rapid Response Team on Hospital-wide Mortality and Code Rates Outside the ICU in a Children’s Hospital
Paul J. Sharek,Layla Parast,Kit Leong,Jodi Coombs,Karla Earnest,Jill Sullivan,Lorry R. Frankel,Stephen J. Roth +7 more
TL;DR: Implementation of an RRT was associated with a statistically significant reduction in hospital-wide mortality rate and code rate outside of the pediatric ICU setting.
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The influence of hemodilution on outcome after hypothermic cardiopulmonary bypass: results of a randomized trial in infants.
Richard A. Jonas,Richard A. Jonas,David Wypij,David Wypij,Stephen J. Roth,David C. Bellinger,David C. Bellinger,Karen J. Visconti,Adré J. du Plessis,Adré J. du Plessis,Howard P. Goodkin,Howard P. Goodkin,Peter C. Laussen,Peter C. Laussen,David M. Farrell,Jodi M. Bartlett,Ellen McGrath,Leonard J Rappaport,Leonard J Rappaport,Emile A. Bacha,Emile A. Bacha,Joseph M. Forbess,Joseph M. Forbess,Pedro J. del Nido,Pedro J. del Nido,John E. Mayer,John E. Mayer,Jane W. Newburger,Jane W. Newburger +28 more
TL;DR: Hemodilution to a hematocrit level in wide use for cardiopulmonary bypass and thought to be safe is associated with adverse perioperative and developmental outcomes in infants.
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Perioperative effects of alpha-stat versus ph-stat strategies for deep hypothermic cardiopulmonary bypass in infants ☆ ☆☆ ★ ★★ ♢
Adré J. du Plessis,Richard A. Jonas,David Wypij,Paul R. Hickey,James Riviello,David L. Wessel,Stephen J. Roth,Frederick A. Burrows,Gene Walter,David M. Farrell,Amy Z. Walsh,Christine A. Plumb,Pedro J. del Nido,Redmond P. Burke,Aldo R. Castaneda,John E. Mayer,Jane W. Newburger +16 more
TL;DR: Use of the pH-stat strategy in infants undergoing deep hypothermic cardiopulmonary bypass was associated with lower postoperative morbidity, shorter recovery time to first electroencephalographic activity, and, in patients with D-transposition, shorter duration of intubation and intensive care unit stay.