Sukhminder Jit Singh Bajwa

TL;DR: In this article, the efficacy and clinical profile of two α-2 adrenergic agonists, dexmedetomidine and clonidine, in epidural anaesthesia with special emphasis on their sedative properties and an ability to provide smooth intra-operative and post-operative analgesia are compared.

TL;DR: The current manuscript discussed the pathophysiology of postsurgical pain including its nature, the various tools for assessment, and the various pharmacological agents available at the authors' disposal to respond to post spinal surgery pain.

TL;DR: In this article, the authors compared the effects of fentanyl and dexmedetomidine when combined with ropivacaine for lower limb orthopedic surgery and found that Dexmedetamidine seems to be a better alternative to fentanyl as an epidural adjuvant as it provides comparable stable hemodynamics, early onset, and establishment of sensory anesthesia, prolonged post-op analgesia, lower consumption of post-operative LA for epidural analgesia and much better sedation levels.

TL;DR: Dexmedetomidine is an excellent drug as it not only decreased the magnitude of haemodynamic response to intubation, surgery and extubation but also decreased the dose of opioids and isoflurane in achieving adequate analgesia and anaesthesia, respectively.

TL;DR: An in-depth analysis of potential risk factors and challenges during administration of anesthesia and possible complications in patients with thyroid disease is aimed at.