S
Susan J. Tofte
Researcher at Oregon Health & Science University
Publications - 24
Citations - 2557
Susan J. Tofte is an academic researcher from Oregon Health & Science University. The author has contributed to research in topics: Atopic dermatitis & Population. The author has an hindex of 17, co-authored 23 publications receiving 2306 citations.
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Journal ArticleDOI
The eczema area and severity index (EASI): assessment of reliability in atopic dermatitis
Jon M. Hanifin,Thurston M,Thurston M,Omoto M,Omoto M,R. Cherill,R. Cherill,Susan J. Tofte,Graeber M,Graeber M +9 more
TL;DR: In this paper, the reliability of the EASI scoring system was evaluated by assessing inter-and intra-observer consistency, and the results indicated that the evaluators assessed the patients consistently across both study days.
Journal ArticleDOI
The prevalence of atopic dermatitis in Oregon schoolchildren.
TL;DR: This study of childhood AD frequency indicates a high prevalence of AD in the United States, comparable to that recently observed from studies in Europe and Japan.
Journal ArticleDOI
Recombinant interferon gamma therapy for atopic dermatitis.
Jon M. Hanifin,Lynda C. Schneider,Donald Y.M. Leung,Charles N. Ellis,Howard S. Jaffe,Allen E. Izu,Louis R. Bucalo,Sue E. Hirabayashi,Susan J. Tofte,Graciela Cantu-Gonzales,Henry Milgrom,Mark Boguniewicz,Kevin D. Cooper +12 more
TL;DR: This study demonstrated that rIFN-gamma given by daily subcutaneous injection over a 12-week period was safe, well accepted, and effective in reducing inflammation, clinical symptoms, and eosinophilia in severe atopic dermatitis.
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Type 4 Phosphodiesterase Inhibitors Have Clinical and In Vitro Anti-inflammatory Effects in Atopic Dermatitis
Jon M. Hanifin,Sai C. Chan,John B. Cheng,Susan J. Tofte,William R. Henderson,Deborah S. Kirby,Ethan S. Weiner +6 more
TL;DR: In vitro assays demonstrated the ability of selective high-potency phosphodiesterase inhibitors to reduce prostaglandin E2, IL-10, and IL-4 production in atopic mononuclear leukocyte cultures, and this in vivo demonstration of anti-inflammatory efficacy may provide a useful alternative to the over-reliance on corticosteroid therapy inAtopic disease.
Journal ArticleDOI
Major Comorbidities of Atopic Dermatitis: Beyond Allergic Disorders
Amy S. Paller,Jennifer C. Jaworski,Eric L. Simpson,Mark Boguniewicz,John J. Russell,Julie Block,Susan J. Tofte,Jeffrey D. Dunn,Steven R. Feldman,Adele R. Clark,Gene Schwartz,Lawrence F. Eichenfield +11 more
TL;DR: Treating physicians should be aware of associations in seeking to alleviate the burden for patients with atopic dermatitis and to improve patient outcomes and to help mitigate the cost and burdens associated with these conditions.