S
Susanne Merkel
Researcher at University of Erlangen-Nuremberg
Publications - 190
Citations - 10024
Susanne Merkel is an academic researcher from University of Erlangen-Nuremberg. The author has contributed to research in topics: Colorectal cancer & Cancer. The author has an hindex of 42, co-authored 166 publications receiving 8077 citations.
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Journal ArticleDOI
Soluble intercellular adhesion molecule-1 is a prognostic marker in colorectal carcinoma
Vera Schellerer,Melanie Langheinrich,Veronika Zver,Robert Grützmann,Michael Stürzl,Olaf Gefeller,Elisabeth Naschberger,Susanne Merkel +7 more
TL;DR: Application of a novel risk score combining CEA/sICAM-1 serum concentrations allows the identification of high-risk groups for poor survival in CRC patients.
Journal ArticleDOI
Survival after surgical treatment of cancer of the rectum.
TL;DR: Tumour-related prognostic factors have the greatest influence on clinical decisions with regard to choice of a therapeutic concept and postoperative long-term global quality of life is similar to the preoperative level.
Journal ArticleDOI
Donor Site Morbidity of Patients Receiving Vertical Rectus Abdominis Myocutaneous Flap for Perineal, Vaginal or Inguinal Reconstruction
Vera Schellerer,Lenka Bartholomé,Melanie Langheinrich,Robert Grützmann,Raymund E. Horch,Susanne Merkel,Klaus Weber +6 more
TL;DR: The use of Vypro® mesh for donor site closure appears to be associated with a low postoperative incidence of complications and can therefore be recommended as a preferred technique.
Journal ArticleDOI
IFN-γ-driven intratumoral microenvironment exhibits superior prognostic effect compared with an IFN-α-driven microenvironment in patients with colon carcinoma.
Sandra Grenz,Elisabeth Naschberger,Susanne Merkel,Nathalie Britzen-Laurent,Ute Schaal,Andreas Konrad,Michael Aigner,Tilman T. Rau,Arndt Hartmann,Roland S. Croner,Werner Hohenberger,Michael Stürzl +11 more
TL;DR: A successful proof-of-principle approach that complex cytokine interaction networks can be dissected in human tissues is described and it is demonstrated that an IFN-γ-driven tumor microenvironment exhibits a superior prognostic effect compared with an IFn-α-driven tumors microenvironment in colon carcinoma.
Journal ArticleDOI
P27 does not predict histopathological response to radiochemotherapy in rectal cancer
Klaus Günther,Arno Dimmler,Franz Rödel,Udo Reulbach,Susanne Merkel,Birgit Bittorf,Klaus E. Matzel,Thomas Papadopoulos,Werner Hohenberger,Rolf Sauer,Claus Rödel +10 more
TL;DR: In this article, the predictive value of the cell-cycle inhibitor p27 kip1 with regard to neoadjuvant RCT response in rectal cancer was evaluated by immunohistochemistry in pretreatment biopsy material.