V
Volodymyr Nikolenko
Researcher at Columbia University
Publications - 20
Citations - 1419
Volodymyr Nikolenko is an academic researcher from Columbia University. The author has contributed to research in topics: Microscope & Spatial light modulator. The author has an hindex of 12, co-authored 19 publications receiving 1340 citations. Previous affiliations of Volodymyr Nikolenko include Howard Hughes Medical Institute.
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Journal ArticleDOI
SLM Microscopy: Scanless Two-Photon Imaging and Photostimulation with Spatial Light Modulators.
Volodymyr Nikolenko,Brendon O. Watson,Roberto Araya,Alan Woodruff,Darcy S. Peterka,Rafael Yuste +5 more
TL;DR: A “scanless” microscope that uses a diffractive spatial light modulator (SLM) to shape an incoming two-photon laser beam into any arbitrary light pattern, which allows the simultaneous imaging or photostimulation of different regions of a sample with three-dimensional precision.
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Two-photon photostimulation and imaging of neural circuits.
TL;DR: An optical method to stimulate individual neurons in brain slices in any arbitrary spatiotemporal pattern using two-photon uncaging of MNI-glutamate with beam multiplexing is introduced, which has single-cell and three-dimensional precision.
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Multiphoton stimulation of neurons.
TL;DR: The combination of multiphoton stimulation and optical probing could enable systematic analysis of circuits and produce sustained depolarization, insensitive to sodium channel blockers yet sensitive to antioxidants.
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Quantitative classification of somatostatin-positive neocortical interneurons identifies three interneuron subtypes
TL;DR: Three groups of cells are revealed: one comprised of Martinotti cells, and two other groups of interneurons with short asymmetric axons targeting layers 2/3 and bending medially, particularly with respect to action potential time course.
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Sodium channels amplify spine potentials.
TL;DR: The data confirm that spines from neocortical pyramidal neurons are electrically isolated from the dendrite and indicate that they have sodium channels and are therefore excitable structures, which could boost synaptic potentials and facilitate action potential backpropagation.