William R. Waddell

TL;DR: A number of problems are described which must be surmounted for the clinical use of liver homotransplantation, based upon experience with 3 patients, and it is thought that the therapy with azathioprine, prednisone, and actinomycin C had forestalled the rejection process.

TL;DR: Four members of a Gardner's syndrome family had rectal and colon polyposis treated with nonsteroid anti‐inflammatory drugs and the residual polyps arose in the rectal mucosa and almost completely disappeared when sulindac was administered.

TL;DR: The effect of sulindac, a nonsteroid antiinflammatory drug, on colon polyposis has been evaluated in seven patients after subtotal colectomy and ileoproctostomy and in four patients with intact colons, finding all polyps were eliminated.

TL;DR: The subsequent behavior of patients who have been brought through a successfully treated rejection crisis suggests the early development of some degree of host-graft adaptation, since the phenomenon of vigorous secondary rejection has been encountered only once.

TL;DR: The use of azathioprine to mitigate rejection increased the early mortality after homotransplantation, 32 of 116 dogs dying within the first week (28 percent) most commonly of pulmonary complications as discussed by the authors.