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Wolf Christian Prall
Researcher at Ludwig Maximilian University of Munich
Publications - 61
Citations - 1731
Wolf Christian Prall is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Mesenchymal stem cell & Medicine. The author has an hindex of 19, co-authored 54 publications receiving 1447 citations. Previous affiliations of Wolf Christian Prall include Paracelsus Private Medical University of Salzburg & University of Düsseldorf.
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Journal ArticleDOI
Uncovering the cellular and molecular changes in tendon stem/progenitor cells attributed to tendon aging and degeneration
Julia Kohler,Cvetan Popov,Barbara Klotz,Paolo Alberton,Wolf Christian Prall,Florian Haasters,Sigrid Müller-Deubert,Regina Ebert,Ludger Klein-Hitpass,Franz Jakob,Matthias Schieker,Denitsa Docheva +11 more
TL;DR: This study provides the first fundamental basis for further exploration into the molecular mechanisms behind tendon aging and degeneration as well as for the selection of novel tendon‐specific therapeutical targets.
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Integrins α2β1 and α11β1 regulate the survival of mesenchymal stem cells on collagen I.
Cvetan Popov,Tamara Radic,Florian Haasters,Wolf Christian Prall,Attila Aszodi,D Gullberg,Matthias Schieker,Denitsa Docheva +7 more
TL;DR: This study describes for the first time that disturbance of α2β1- or α11 β1-mediated interactions to collagen I results in the cell death of MSCs and urges for further investigations examining the impact of M SCs in bone conditions with abnormal collagen I.
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Diagnosis and treatment of acute ankle injuries: development of an evidence-based algorithm
Hans Polzer,Karl-Georg Kanz,Wolf Christian Prall,Florian Haasters,Ben Ockert,Wolf Mutschler,S. Grote +6 more
TL;DR: An applicable and evidence-based, step by step, decision pathway for the diagnosis and treatment of acute ankle injuries is presented, which can be implemented in any emergency department or doctor's practice and provides quality assurance for the patient and promotes confidence in the attending physician.
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Morphological and immunocytochemical characteristics indicate the yield of early progenitors and represent a quality control for human mesenchymal stem cell culturing.
Florian Haasters,Wolf Christian Prall,David Anz,Carole Bourquin,Christoph Pautke,Stefan Endres,Wolf Mutschler,Denitsa Docheva,Matthias Schieker +8 more
TL;DR: It is revealed that among the recently suggested surface markers, CD73 is the most sensitive, as it seems to be down‐regulated in the early stages of differentiation, and thereby provides a quality control approach for hMSC culturing.
Journal ArticleDOI
IKK-2 is required for TNF-α-induced invasion and proliferation of human mesenchymal stem cells
Wolfgang Böcker,Denitsa Docheva,Wolf Christian Prall,Virginia Egea,Emmanouil Pappou,Oliver Roßmann,Cvetan Popov,Wolf Mutschler,Christian Ries,Matthias Schieker +9 more
TL;DR: The data provide evidence that this signal transduction pathway is implicated in TNF-α-mediated invasion and proliferation of hMSCs, and demonstrate that hMSC recruitment to sites of tissue injury may, at least in part, be regulated by the NF-κB signalTransduction pathway.