Xin Xu

TL;DR: A broad class of family‐based association tests that are adjusted for admixture; use either dichotomous or measured phenotypes; accommodate phenotype‐unknown subjects; use nuclear families, sibships or a combination of the two, permit multiple nuclear families from a single pedigree; incorporate di‐ or multi‐allelic marker data; and permit adjustment for covariates and gene‐by‐environment interactions are described.

TL;DR: It is shown that the RC-TDT is equivalent to a special case of the FBAT method, and it is generalised to dominant, recessive and multi-allelic marker codings.

TL;DR: The proposed weighted conditional approach extends the method described in Rabinowitz and Laird to multiple markers and provides haplotype tests for family‐based studies that are efficient and robust to population admixture, phenotype distribution specification, and ascertainment based on phenotypes.

TL;DR: The rate of contraction mutations increases exponentially with allele size, whereas the rate of expansion mutations is constant across the entire allele distribution, offering an explanation for the stationary allele distribution of microsatellites.

TL;DR: Initial results of serological surveillance in China provide valuable data for estimation of the cumulative prevalence of SARS-CoV-2 infection in the general population and whether these results are generalizable to other populations and geographic locations.