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Ya'nan Yang
Researcher at Fudan University
Publications - 6
Citations - 265
Ya'nan Yang is an academic researcher from Fudan University. The author has contributed to research in topics: Cancer & Metastasis. The author has an hindex of 1, co-authored 2 publications receiving 143 citations.
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Journal ArticleDOI
Epigenetic regulation of cancer progression by EZH2: from biological insights to therapeutic potential.
TL;DR: The molecular functions of EZH2 are discussed, recent findings regarding the physiological functions and related regulation of E zeste homolog 2 in cancer pathogenesis are highlighted, and the emerging roles of EzH2 in tumor immunity are summarized.
Journal ArticleDOI
Amplification and expression of c-MET correlate with poor prognosis of patients with gastric cancer and upregulate the expression of PDL1.
Ya'nan Yang,Chenchen Wang,Congqi Dai,Xinyang Liu,Wenhua Li,Mingzhu Huang,Xiaoying Zhao,Dongmei Ji,Jin Li,Jin Li,Weijian Guo +10 more
TL;DR: In this article, the authors examined the amplification, expression, and the prognostic value of mesenchymal-epithelial transition (MET) inhibitors, human epidermal growth factor receptor 2 (HER2), and programmed cell death ligand 1 (PDL1), together with the correlations among them in a large cohort of Chinese samples.
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Integrated DNA and RNA sequencing reveals early drivers involved in metastasis of gastric cancer
Jieyun Zhang,Fatao Liu,Ya'nan Yang,Nuoya Yu,Xiaoling Weng,Yu Yang,Zhe Gong,Shenglin Huang,Lu Gan,Sijie Sun,Xiaowei Zhang,Yiwei Gong,Yun Liu,Weijian Guo +13 more
TL;DR: Wang et al. as discussed by the authors conducted an integrative genomic analysis on Gastric cancer and identified early drivers lead to metastasis, and identified 176 candidate prometastatic mutations by WES and selected 8 genes for following TES.
Journal ArticleDOI
Integrated DNA and RNA sequencing reveals early drivers involved in metastasis of gastric cancer
Jieyun Zhang,Fatao Liu,Ya'nan Yang,Nuoya Yu,Xiaoling Weng,Yu Yang,Zhe Gong,Shenglin Huang,Lurui Gan,Sijie Sun,Xiaowei Zhang,Yiwei Gong,Yun Liu,Weijian Guo +13 more
TL;DR: Wang et al. as discussed by the authors conducted an integrative genomic analysis on Gastric cancer and identified early drivers lead to metastasis, and identified 176 candidate prometastatic mutations by WES and selected 8 genes for following TES.
Journal ArticleDOI
Induction Chemotherapy Followed by Primary Tumor Resection Did Not Bring Survival Benefits in Colon Cancer Patients With Asymptomatic Primary Lesion and Synchronous Unresectable Metastases
Mingzhu Huang,Ya'nan Yang,Qingguo Li,Chenchen Wang,Lei Liang,Xiao-Dong Zhu,Wen Zhang,Zhiyu Chen,Dan-Dan Huang,Wenhua Li,Xiaowei Zhang,Xiaoying Zhao,Li-Xin Qiu,Qirong Geng,Nuoya Yu,Wen-jun Du,Sijie Sun,Xuedan Sheng,Xinxiang Li,Weijian Guo +19 more
TL;DR: PTR after induction chemotherapy could not bring survival benefits for colon cancer patients with unresectable metastases, and it is not recommended routinely.