Y
Yuan Soon Ho
Researcher at Taipei Medical University
Publications - 160
Citations - 7212
Yuan Soon Ho is an academic researcher from Taipei Medical University. The author has contributed to research in topics: Apoptosis & Cancer cell. The author has an hindex of 42, co-authored 155 publications receiving 6411 citations. Previous affiliations of Yuan Soon Ho include National Taiwan University & Taipei Medical University Hospital.
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Journal ArticleDOI
Survivin-Mediated Cancer Cell Migration Through GRP78 and Epithelial-Mesenchymal Transition (EMT) Marker Expression in Mahlavu Cells
Cheng Jeng Tai,Hung Chin-Sheng,Hung Chin-Sheng,Li Jen Kuo,Li Jen Kuo,Po Li Wei,Hsuan Hsuan Lu,Hsin An Chen,Tsan Zon Liu,Jun Jen Liu,Der Zen Liu,Yuan Soon Ho,Chih Hsiung Wu,Yu Jia Chang +13 more
TL;DR: The knockdown of Survivin expression may enhance cancer metastasis through the downregulation of GRP78 and upregulation of vimentin expression and the mechanism of enhanced cell migration caused by decreased survivin expression is mediated through theDownregulation of glucose-regulated protein 78 (GRP78) and theUpregulation of the epithelial-mesenchymal transition (EMT) marker, vimentsin.
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Induction of apoptosis and cell-cycle arrest in human colon cancer cells by meclizine.
Jiunn Chang Lin,Yuan Soon Ho,Jie Jen Lee,Chien-Liang Liu,Chien-Liang Liu,Tsen Long Yang,Chih Hsiung Wu,Chih Hsiung Wu +7 more
TL;DR: The molecular basis of MEC-induced apoptosis and cell-cycle arrest in human colon cancer cells is provided and the percentage of COLO 205 cells arrested at G0/G1 phase increased dose- dependency.
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Thiol antioxidant and thiol-reducing agents attenuate 15-deoxy-Δ12,14-prostaglandin J2-induced heme oxygenase-1 expression
Jean-Dean Liu,Jean-Dean Liu,Shu Huei Tsai,Shyr Yi Lin,Shyr Yi Lin,Yuan Soon Ho,Ling Fang Hung,Shiann Pan,Shiann Pan,Feng Ming Ho,Chun Mao Lin,Yu Chih Liang +11 more
TL;DR: It is suggested that thiol antioxidant and reducing agents attenuate the expression of HO-1 induced by 15d-PGJ(2), and that the cellular thiol-disulfide redox status may be linked toHO-1 activation.
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Silencing of glucose-regulated protein 78 (GRP78) enhances cell migration through the upregulation of vimentin in hepatocellular carcinoma cells.
Po-Li Wei,Li Jen Kuo,Weu Wang,Feng-Yen Lin,Hui-Hsiung Liu,Tseng How,Yuan Soon Ho,Ming-Te Huang,Chih-Hsiung Wu,Yu Jia Chang +9 more
TL;DR: Glucose-regulated protein 78 silencing in HCC cells may enhance cell migration through the increase of vimentin expression, indicating that vimentsin expression levels modulated the cell migratory ability.
Journal ArticleDOI
Development and characterization of docetaxel-loaded lecithin-stabilized micellar drug delivery system (L sb MDDs) for improving the therapeutic efficacy and reducing systemic toxicity
Chia Yu Su,Jun Jen Liu,Yuan Soon Ho,Yi-You Huang,Vincent H.S. Chang,Der Zen Liu,Ling Chun Chen,Hsiu O. Ho,Ming Thau Sheu,Ming Thau Sheu +9 more
TL;DR: The LsbMDDs could be a promising high drug‐loaded nanocarrier for delivering hydrophobic chemotherapeutic agents that can enhance the efficacy of chemotherapy and reduce systemic toxicity.