Zhiyun Chen

TL;DR: Novel surface-engineered gold nanorods used as promising DNA vaccine adjuvant for HIV treatment and shed light on the rational design of low-toxic nanomaterials as a versatile platform for vaccine nanoadjuvants/delivery systems are reported.

TL;DR: The present review summarizes the potential of fullerenes as tumor theranostics agents and their possible underlying mechanisms are discussed.

TL;DR: Gd-metallofullerenol is identified as a kind of non-toxic CSC specific inhibitors with significant therapeutic potential and indicates that nanomaterials can be engineered to directly target CSCs.

TL;DR: In vivo and in vitro studies demonstrate that MWCNTs stimulate pulmonary fibrotic responses such as fibroblast proliferation and collagen deposition in a TGF-β/Smad-dependent manner and suggest that tube length acts as an important factor in M WCNT-induced macrophage activation and subsequent TGF -β1 secretion.

TL;DR: The underlying mechanisms by which fullerenol-based formulation induces polyvalent immune responses are involved in activating multiple TLRs signaling pathways and inducing TEM -biased immunity to combat the infection at early stage.