Showing papers by "G. B. Pant University of Agriculture and Technology published in 1970"

Chemical Composition, Anti-inflammatory, Analgesic, Antipyretic, Myorelaxant, Antibacterial and Antifungal activity of Rabdosia rugosus Wall. (Syn. Plectranthus rugosus Wall.)

Abstract: For the present investigation Rabdosia rugosus Wall. Syn. Plectranthus rugosus Wall. was collected from Pancheshwar, Uttarakhand on the way to Badrinath. The GC and GC-MS analysis, revealed the presence of more than forty compounds out of which 35 compounds were identified amounting to 97.3% of the total oil. The essential oil of R. rugosus was rich in sesquiterpinoids (~90%) and was poor in monoterpenoids (8.1%). α-bisabolol (41.9%) was the major constituent of the oil and the other identified major compounds were germacrene-D (9.7%), β-caryophyllene (7.6%), dehydroabietane (5.2%), ar-curcumene (5.0), trans-ferruginol (3.3%), α-cadinol (3.2%), T-muurolol (2.3%), p-Cymene (3.2%) and γ-terpinene (2.0%). The essential oil of Rabdosia rugosus showed insignificant anti-inflammatory and analgesic activity but shows significant antipyretic, myorelaxant and antimicrobial activity.