Institution
Gurudas College
About: Gurudas College is a based out in . It is known for research contribution in the topics: Neutrino & Supply chain. The organization has 42 authors who have published 136 publications receiving 2654 citations.
Topics: Neutrino, Supply chain, Yukawa potential, Lepton, Neutrino oscillation
Papers published on a yearly basis
Papers
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TL;DR: There is a large variation in the antimicrobial activity of some natural honeys, which is due to spatial and temporal variation in sources of nectar, and identification and characterization of the active principle(s) may provide valuable information on the quality and possible therapeutic potential of honeys.
Abstract: Indeed, medicinal importance of honey has been documented in the world's oldest medical literatures, and since the ancient times, it has been known to possess antimicrobial property as well as wound-healing activity. The healing property of honey is due to the fact that it offers antibacterial activity, maintains a moist wound condition, and its high viscosity helps to provide a protective barrier to prevent infection. Its immunomodulatory property is relevant to wound repair too. The antimicrobial activity in most honeys is due to the enzymatic production of hydrogen peroxide. However, another kind of honey, called non-peroxide honey (viz., manuka honey), displays significant antibacterial effects even when the hydrogen peroxide activity is blocked. Its mechanism may be related to the low pH level of honey and its high sugar content (high osmolarity) that is enough to hinder the growth of microbes. The medical grade honeys have potent in vitro bactericidal activity against antibiotic-resistant bacteria causing several life-threatening infections to humans. But, there is a large variation in the antimicrobial activity of some natural honeys, which is due to spatial and temporal variation in sources of nectar. Thus, identification and characterization of the active principle(s) may provide valuable information on the quality and possible therapeutic potential of honeys (against several health disorders of humans), and hence we discussed the medicinal property of honeys with emphasis on their antibacterial activities.
585 citations
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TL;DR: Coconut, Cocos nucifera L., is a tree that is cultivated for its multiple utilities, mainly for its nutritional and medicinal values as mentioned in this paper. But, it is not suitable for the use in agriculture.
316 citations
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TL;DR: In this paper, a wearable bio-inspired piezoelectric pressure sensor was designed from structurally stable fish gelatin nanofibers (GNFs) using large area compatible electrospining technology.
173 citations
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TL;DR: Five phytochemicals, which belong to flavonoid and anthraquinone subclass, have been selected as small molecules in molecular docking study of spike protein of SARS-CoV2 with its human receptor ACE2 molecule and their molecular binding sites on spike protein bound structure with its receptor have been analyzed.
Abstract: Angiotensin converting enzyme 2 (ACE2) (EC:3.4.17.23) is a transmembrane protein which is considered as a receptor for spike protein binding of novel coronavirus (SARS-CoV2). Since no specific medication is available to treat COVID-19, designing of new drug is important and essential. In this regard, in silico method plays an important role, as it is rapid and cost effective compared to the trial and error methods using experimental studies. Natural products are safe and easily available to treat coronavirus affected patients, in the present alarming situation. In this paper five phytochemicals, which belong to flavonoid and anthraquinone subclass, have been selected as small molecules in molecular docking study of spike protein of SARS-CoV2 with its human receptor ACE2 molecule. Their molecular binding sites on spike protein bound structure with its receptor have been analyzed. From this analysis, hesperidin, emodin and chrysin are selected as competent natural products from both Indian and Chinese medicinal plants, to treat COVID-19. Among them, the phytochemical hesperidin can bind with ACE2 protein and bound structure of ACE2 protein and spike protein of SARS-CoV2 noncompetitively. The binding sites of ACE2 protein for spike protein and hesperidin, are located in different parts of ACE2 protein. Ligand spike protein causes conformational change in three-dimensional structure of protein ACE2, which is confirmed by molecular docking and molecular dynamics studies. This compound modulates the binding energy of bound structure of ACE2 and spike protein. This result indicates that due to presence of hesperidin, the bound structure of ACE2 and spike protein fragment becomes unstable. As a result, this natural product can impart antiviral activity in SARS CoV2 infection. The antiviral activity of these five natural compounds are further experimentally validated with QSAR study.
163 citations
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TL;DR: This review represents an updated scenario on the transmission cycle, epidemiology, clinical features and pathogenicity, diagnosis and treatment, and prevention and control measures of a cestode parasite Echincoccus granulosus causing cystic echinococcosis in humans and animal CE.
147 citations
Authors
Showing all 42 results
Name | H-index | Papers | Citations |
---|---|---|---|
Shyamapada Mandal | 20 | 77 | 2223 |
Anirban Biswas | 15 | 34 | 702 |
Partha Chowdhury | 14 | 34 | 521 |
T. Maiti | 14 | 28 | 721 |
Santanu Paul | 12 | 45 | 370 |
Biswajit Adhikary | 11 | 19 | 432 |
Sumana Gangopadhyay | 10 | 24 | 208 |
Rupayan Bhattacharya | 8 | 27 | 284 |
Mandira Sinha | 7 | 14 | 163 |
P. Brahma | 7 | 9 | 134 |
Pratip Bhattacharyya | 6 | 14 | 196 |
Ruma Ray | 6 | 16 | 100 |
Priya K. Gopal | 6 | 15 | 139 |
Abhra Giri | 6 | 13 | 140 |
Biswajit Adhikary | 5 | 5 | 185 |