Institution
Johns Hopkins Bayview Medical Center
Healthcare•Baltimore, Maryland, United States•
About: Johns Hopkins Bayview Medical Center is a healthcare organization based out in Baltimore, Maryland, United States. It is known for research contribution in the topics: Population & Health care. The organization has 1547 authors who have published 1851 publications receiving 77110 citations. The organization is also known as: Francis Scott Key Medical Center & Baltimore City Hospitals.
Topics: Population, Health care, Dementia, MEDLINE, Randomized controlled trial
Papers published on a yearly basis
Papers
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TL;DR: The Clinician’s Guide to Prevention and Treatment of Osteoporosis was developed by an expert committee of the National Osteiporosis Foundation in collaboration with a multispecialty council of medical experts in the field of bone health convened by NOF.
Abstract: The Clinician’s Guide to Prevention and Treatment of Osteoporosis was developed by an expert committee of the National Osteoporosis Foundation (NOF) in collaboration with a multispecialty council of medical experts in the field of bone health convened by NOF. Readers are urged to consult current prescribing information on any drug, device, or procedure discussed in this publication.
2,926 citations
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TL;DR: Modification of the criteria for the diagnosis of restless legs syndrome is modified to better reflect that increased body of knowledge, as well as to clarify slight confusion with the wording of the original criteria.
2,834 citations
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TL;DR: Why Aβ accumulates in the brains of elderly individuals is unclear but could relate to changes in APP metabolism or Aβ elimination, which will be crucial to the development of therapeutic targets to treat AD.
Abstract: Alzheimer's disease (AD), the leading cause of dementia worldwide, is characterized by the accumulation of the β-amyloid peptide (Aβ) within the brain along with hyperphosphorylated and cleaved forms of the microtubule-associated protein tau. Genetic, biochemical, and behavioral research suggest that physiologic generation of the neurotoxic Aβ peptide from sequential amyloid precursor protein (APP) proteolysis is the crucial step in the development of AD. APP is a single-pass transmembrane protein expressed at high levels in the brain and metabolized in a rapid and highly complex fashion by a series of sequential proteases, including the intramembranous γ-secretase complex, which also process other key regulatory molecules. Why Aβ accumulates in the brains of elderly individuals is unclear but could relate to changes in APP metabolism or Aβ elimination. Lessons learned from biochemical and genetic studies of APP processing will be crucial to the development of therapeutic targets to treat AD.
1,486 citations
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TL;DR: All tissues and organs were reconstructed as three-dimensional unstructured triangulated surface objects, yielding high precision images of individual features of the body, which greatly enhances the meshing flexibility and the accuracy in comparison with the traditional voxel-based representation of anatomical models.
Abstract: The objective of this study was to develop anatomically correct whole body human models of an adult male (34 years old), an adult female (26 years old) and two children (an 11-year-old girl and a six-year-old boy) for the optimized evaluation of electromagnetic exposure. These four models are referred to as the Virtual Family. They are based on high resolution magnetic resonance (MR) images of healthy volunteers. More than 80 different tissue types were distinguished during the segmentation. To improve the accuracy and the effectiveness of the segmentation, a novel semi-automated tool was used to analyze and segment the data. All tissues and organs were reconstructed as three-dimensional (3D) unstructured triangulated surface objects, yielding high precision images of individual features of the body. This greatly enhances the meshing flexibility and the accuracy with respect to thin tissue layers and small organs in comparison with the traditional voxel-based representation of anatomical models. Conformal computational techniques were also applied. The techniques and tools developed in this study can be used to more effectively develop future models and further improve the accuracy of the models for various applications. For research purposes, the four models are provided for free to the scientific community.
1,347 citations
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Institute for Health Metrics and Evaluation1, University of Washington2, University College London3, Qatar Foundation4, Mashhad University of Medical Sciences5, University of Otago6, Queen Elizabeth Hospital Birmingham7, University of Melbourne8, Johns Hopkins Bayview Medical Center9, Universiti Sains Malaysia10, Burnet Institute11, George Mason University12, Dartmouth College13, Tehran University of Medical Sciences14, University of California, San Diego15, University of Bristol16, University of Texas Southwestern Medical Center17, Environment Agency18, University of Chicago19, Erasmus University Rotterdam20, Case Western Reserve University21, Cancer Treatment Centers of America22, Bayer23, Tufts Medical Center24, Stanford University25, National Research University – Higher School of Economics26, Centers for Disease Control and Prevention27, Jackson State University28, Wuhan University29, Mansoura University30, Imperial College London31
TL;DR: The enormous health loss attributable to viral hepatitis, and the availability of effective vaccines and treatments, suggests an important opportunity to improve public health.
1,081 citations
Authors
Showing all 1560 results
Name | H-index | Papers | Citations |
---|---|---|---|
George Howard | 112 | 791 | 60770 |
Alan W. Partin | 111 | 710 | 54213 |
Constantine G. Lyketsos | 111 | 567 | 43932 |
Louis R. Kavoussi | 95 | 544 | 31830 |
Michael J. Levy | 94 | 1029 | 37843 |
Richard P. Allen | 92 | 379 | 30312 |
Elaine Larson | 88 | 674 | 31100 |
Martin H. Steinberg | 87 | 468 | 28333 |
Ellen J. MacKenzie | 86 | 267 | 26225 |
John H. Stone | 85 | 472 | 34929 |
Donald K. Ingram | 85 | 402 | 33358 |
Todd J. Albert | 83 | 512 | 23892 |
Ichiro Tsuji | 81 | 607 | 26497 |
Rebecca Gelman | 81 | 283 | 34736 |
Lee A. Fleisher | 79 | 355 | 32800 |