Ragas Dental College & Hospital

About: Ragas Dental College & Hospital is a healthcare organization based out in Chennai, India. It is known for research contribution in the topics: Population & Leukoplakia. The organization has 542 authors who have published 420 publications receiving 6139 citations.

Chemical and physical basics of routine formaldehyde fixation.

Abstract: Formaldehyde is the widely employed fixative that has been studied for decades. The chemistry of fixation has been studied widely since the early 20 th century. However, very few studies have been focused on the actual physics/chemistry aspect of process of this fixation. This article attempts to explain the chemistry of formaldehyde fixation and also to study the physical aspects involved in the fixation. The factors involved in the fixation process are discussed using well documented mathematical and physical formulae. The deeper understanding of these factors will enable pathologist to optimize the factors and use them in their favor.

Oral lichen planus: An update on pathogenesis and treatment

Abstract: Oral lichen planus (OLP) is a chronic inflammatory disease that affects the mucus membrane of the oral cavity. It is a T-cell mediated autoimmune disease in which the cytotoxic CD8+ T cells trigger apoptosis of the basal cells of the oral epithelium. Several antigen-specific and nonspecific inflammatory mechanisms have been put forward to explain the accumulation and homing of CD8+ T cells subepithelially and the subsequent keratinocyte apoptosis. A wide spectrum of treatment modalities is available, from topical corticosteroids to laser ablation of the lesion. In this review, we discuss the various concepts in the pathogenesis and current treatment modalities of OLP.

Compatibility of Nonoriginal Abutments With Implants: Evaluation of Microgap at the Implant-Abutment Interface, With Original and Nonoriginal Abutments

Abstract: Purpose The purpose of this study was to evaluate the fit of nonoriginal abutments to implants at the implant abutment junction. Materials and methods Twenty titanium implants from a single manufacturer were randomly divided into 2 groups of ten each. Ten titanium premachined original abutments (group I) and ten titanium premachined nonoriginal abutments (from different manufacturer-group II) were connected to the implants with the recommended manufacturer torque level and then embedded into autopolymerizing clear acrylic resin blocks. After overnight curing, these blocks were vertically sectioned using water jet sectioning machine and evaluated under scanning electron microscope following the sequential cleaning procedures. The microgap at the implant-abutment interface for all the samples was measured using pixel counting software and subjected to statistical analysis using nonparametric Mann-Whitney U test. Results The mean microgap at the implant-abutment interface at the external, middle, and internal points was 1.597, 1.399, and 1.831 µm, respectively, for group I and 2.395, 2.488, and 3.339 µm, respectively, for group II samples. Nonparametric Mann-Whitney U test showed statistically significant difference between 2 groups at the midpoint for the nonoriginal abutments compared with the original ones. Conclusion Within the limitations of the study, the mean microgap at the implant-abutment interface at the platform level at the external, middle, and internal points for both original abutments and nonoriginal abutments was found to be within clinically acceptable limits.

Evaluation of the marginal fit of a zirconia ceramic computer-aided machined (CAM) crown system

Abstract: Statement of problem The marginal fit of crowns is a concern for clinicians, and there is no conclusive evidence of any one margin configuration yielding better results than others in terms of marginal fit. Purpose The purpose of this study was to evaluate the marginal fit with respect to gap and overhang of Y-TZP (yttria-stabilized tetragonal zirconia polycrystals) ceramic crowns and compare them with lithium disilicate pressable and complete metal crowns. The influence of margin configuration on the marginal fit was also evaluated. Material and methods Impressions were made of premolar dies prepared with shoulders or chamfers with a 20-degree total occlusal convergence (n=30). Type IV stone dies were then distributed into test groups (n=10) for the fabrication of Cercon Y-TZP, IPS Empress II, and complete metal (noble type IV alloy) crowns. The crowns were then subjected to marginal gap and overhang evaluation at 6 designated margin locations using a computerized digital image analysis system. The data were calculated and statistically analyzed using 2-way ANOVA and Bonferroni post hoc tests (α=.05). Results The overall mean (SD) marginal gap at the marginal opening for the crowns was 66.4 (42.2) μm for Cercon, 36.6 (32.1) μm for IPS Empress II, and 37.1 (22.3) μm for complete metal (control). Overall mean (SD) overhang was −15.2 (47.5) μm for Cercon, −22.1 (34.7) μm for IPS Empress II, and 30.9 (31.3) μm for complete metal (control). The ANOVA revealed significant effects by material and no significant effects by marginal configuration for marginal gap. There were significant differences in the marginal overhang values between the 2 margins, but no significant differences were found between the material groups for overhang. Conclusions The Cercon system showed significantly larger ( P P

Prevalence of oral lesions in relation to habits: Cross-sectional study in South India.

Abstract: BACKGROUND: Smoking, drinking and chewing tobacco product, common habits in India have been positively associated with oral lesions. No study has been conducted in this part of Tamilnadu regarding the prevalence of oral lesions in relation to habits. METHODS: A hospital based cross-sectional study was carried out at Ragas Dental College, Chennai. Already existing data of two thousand and seventeen consecutive patients from sub-urban areas of Chennai, who attended the outpatient department, at Ragas Dental College, for dental complaints during a period of three months in 2004, who underwent oral examination and interviewer based questionnaire was used. RESULTS: Oral soft tissue lesions were found in 4.1% of the study subjects. The prevalence of leukoplakia, OSF and oral lichen planus was 0.59%, 0.55%, and 0.15% respectively. The prevalence of smoking, drinking alcoholic beverages and chewing was 15.02%, 8.78% and 6.99% respectively. Smoking and chewing were significant predictors of leukoplakia in this population. DISCUSSION: The prevalence of leukoplakia, OSF and oral lichen planus in our study population is similar to those found in other populations. The prevalence of consumption of alcoholic beverages in our study population was higher when compared to the Indian National Sample Survey study. However the prevalence of smoking and chewing was found to be lower. Smokers were more likely to develop smoker's melanosis compared to other lesions. Among those who consumed alcoholic beverages alone, the prevalence of leukoplakia was higher compared to other lesions. OSF was the most prevalent lesion among those who chewed panmasala or gutkha or betel quid with or without tobacco.