University of Bristol

About: University of Bristol is a education organization based out in Bristol, United Kingdom. It is known for research contribution in the topics: Population & Context (language use). The organization has 44253 authors who have published 113186 publications receiving 4947181 citations. The organization is also known as: Bris..

Power failure: why small sample size undermines the reliability of neuroscience

Abstract: A study with low statistical power has a reduced chance of detecting a true effect, but it is less well appreciated that low power also reduces the likelihood that a statistically significant result reflects a true effect. Here, we show that the average statistical power of studies in the neurosciences is very low. The consequences of this include overestimates of effect size and low reproducibility of results. There are also ethical dimensions to this problem, as unreliable research is inefficient and wasteful. Improving reproducibility in neuroscience is a key priority and requires attention to well-established but often ignored methodological principles.

Significance of Electromagnetic Potentials in the Quantum Theory

Abstract: In this paper, we discuss some interesting properties of the electromagnetic potentials in the quantum domain. We shall show that, contrary to the conclusions of classical mechanics, there exist effects of potentials on charged particles, even in the region where all the fields (and therefore the forces on the particles) vanish. We shall then discuss possible experiments to test these conclusions; and, finally, we shall suggest further possible developments in the interpretation of the potentials.

Estimating the reproducibility of psychological science

Abstract: Reproducibility is a defining feature of science, but the extent to which it characterizes current research is unknown. We conducted replications of 100 experimental and correlational studies published in three psychology journals using high-powered designs and original materials when available. Replication effects were half the magnitude of original effects, representing a substantial decline. Ninety-seven percent of original studies had statistically significant results. Thirty-six percent of replications had statistically significant results; 47% of original effect sizes were in the 95% confidence interval of the replication effect size; 39% of effects were subjectively rated to have replicated the original result; and if no bias in original results is assumed, combining original and replication results left 68% with statistically significant effects. Correlational tests suggest that replication success was better predicted by the strength of original evidence than by characteristics of the original and replication teams.