Institution
University of Iowa
Education•Iowa City, Iowa, United States•
About: University of Iowa is a education organization based out in Iowa City, Iowa, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 49229 authors who have published 109171 publications receiving 5021465 citations. The organization is also known as: UI & The University of Iowa.
Topics: Population, Poison control, Large Hadron Collider, Health care, Gene
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University College London1, University of Glasgow2, University of Cambridge3, Utrecht University4, University of Groningen5, University of Pennsylvania6, University of London7, University of Edinburgh8, Imperial College London9, Jackson State University10, Lithuanian University of Health Sciences11, Jagiellonian University12, Russian Academy13, University of Milan14, Karolinska Institutet15, Translational Genomics Research Institute16, Leiden University17, Memorial Hospital of Rhode Island18, University of Iowa19, University of Oslo20, University of Texas at San Antonio21, Veterans Health Administration22, Cornell University23, University of Sydney24, University of Paris25, Harvard University26, St George's, University of London27, University of Minnesota28, University of Texas Health Science Center at Houston29, University of Washington30, University of Vermont31, GlaxoSmithKline32, Broad Institute33, Children's Hospital Oakland Research Institute34, University of North Carolina at Chapel Hill35, University of Bristol36, Johns Hopkins University37, Cardiff University38, University of Mississippi39, Fred Hutchinson Cancer Research Center40
TL;DR: The increased risk of type 2 diabetes noted with statins is at least partially explained by HMGCR inhibition.
545 citations
TL;DR: Patients with stroke have an increased incidence of obstructive sleep apnea compared with normal sex- and age-matched control subjects, which may have predisposed these patients to stroke.
Abstract: Background and Purpose We aimed to prospectively determine whether the incidence of obstructive sleep apnea in patients with recent stroke was significantly different from that of a sex- and age-matched control group with no major medical problems. Methods We prospectively performed overnight polysomnography in 24 patients with a recent stroke (13 men and 11 women; mean age [±SD], 64.6±10.4 years) and 27 subjects without stroke (13 men and 14 women; mean age, 61.6±8.8 years). Patients with either ischemic or hemorrhagic stroke were entered into this study. Polysomnographic evaluations were performed within approximately 2 to 5 weeks after each patient’s stroke. Results Obstructive sleep apnea was found in 10 of 13 men with stroke (77%) and in only 3 of 13 male subjects without stroke (23%) (P=.0169). Seven of 11 women with stroke (64%) had obstructive sleep apnea, while only 2 of 14 female subjects without stroke (14%) had obstructive sleep apnea (P=.0168). For men with stroke, the mean apnea/hypopnea ind...
545 citations
TL;DR: This study tested the hypothesis that interfacial degradation of resin-dentin bonds may be prevented or delayed by the application of chlorhexidine (CHX), a matrix metalloproteinase inhibitor, to dentin after phosphoric acid-etching.
Abstract: Host-derived proteases have been reported to degrade the collagen matrix of incompletely-resin-infiltrated dentin. This study tested the hypothesis that interfacial degradation of resin-dentin bonds may be prevented or delayed by the application of chlorhexidine (CHX), a matrix metalloproteinase inhibitor, to dentin after phosphoric acid-etching. Contralateral pairs of resin-bonded Class I restorations in non-carious third molars were kept under intra-oral function for 14 months. Preservation of resin-dentin bonds was assessed by microtensile bond strength tests and TEM examination. In vivo bond strength remained stable in the CHX-treated specimens, while bond strength decreased significantly in control teeth. Resin-infiltrated dentin in CHX-treated specimens exhibited normal structural integrity of the collagen network. Conversely, progressive disintegration of the fibrillar network was identified in control specimens. Auto-degradation of collagen matrices can occur in resin-infiltrated dentin, but may be prevented by the application of a synthetic protease inhibitor, such as chlorhexidine.
544 citations
TL;DR: Sina no study reports systematically colkctcd muscle liber length in all lower limb muscles, including hip muscles, so the following work is conducted.
544 citations
544 citations
Authors
Showing all 49661 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Stephen V. Faraone | 188 | 1427 | 140298 |
| Jie Zhang | 178 | 4857 | 221720 |
| D. M. Strom | 176 | 3167 | 194314 |
| Bradley T. Hyman | 169 | 765 | 136098 |
| John H. Seinfeld | 165 | 921 | 114911 |
| David Jonathan Hofman | 159 | 1407 | 140442 |
| Stephen J. O'Brien | 153 | 1062 | 93025 |
| John T. Cacioppo | 147 | 477 | 110223 |
| Mark Raymond Adams | 147 | 1187 | 135038 |
| E. L. Barberio | 143 | 1605 | 115709 |
| Andrew Ivanov | 142 | 1812 | 97390 |
| Stephen J. Lippard | 141 | 1201 | 89269 |
| Russell Richard Betts | 140 | 1323 | 95678 |
| Barry Blumenfeld | 140 | 1909 | 105694 |
| Marcus Hohlmann | 140 | 1356 | 94739 |