Journal ArticleDOI
A new method for detecting anaerobic threshold by gas exchange
TLDR
From incremental exercise tests on 10 subjects, the point of excess CO2 output (AT) predicted closely the lactate and HCO-3 thresholds and could be more reliably determined by the V-slope method.Abstract:
Excess CO2 is generated when lactate is increased during exercise because its [H+] is buffered primarily by HCO-3 (22 ml for each meq of lactic acid). We developed a method to detect the anaerobic threshold (AT), using computerized regression analysis of the slopes of the CO2 uptake (VCO2) vs. O2 uptake (VO2) plot, which detects the beginning of the excess CO2 output generated from the buffering of [H+], termed the V-slope method. From incremental exercise tests on 10 subjects, the point of excess CO2 output (AT) predicted closely the lactate and HCO-3 thresholds. The mean gas exchange AT was found to correspond to a small increment of lactate above the mathematically defined lactate threshold [0.50 +/- 0.34 (SD) meq/l] and not to differ significantly from the estimated HCO-3 threshold. The mean VO2 at AT computed by the V-slope analysis did not differ significantly from the mean value determined by a panel of six experienced reviewers using traditional visual methods, but the AT could be more reliably determined by the V-slope method. The respiratory compensation point, detected separately by examining the minute ventilation vs. VCO2 plot, was consistently higher than the AT (2.51 +/- 0.42 vs. 1.83 +/- 0.30 l/min of VO2). This method for determining the AT has significant advantages over others that depend on regular breathing pattern and respiratory chemosensitivity.read more
Citations
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Clinician’s Guide to Cardiopulmonary Exercise Testing in Adults A Scientific Statement From the American Heart Association
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Randomized, Controlled Trial of Long-Term Moderate Exercise Training in Chronic Heart Failure: Effects on Functional Capacity, Quality of Life, and Clinical Outcome
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References
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Journal ArticleDOI
Anaerobic threshold and respiratory gas exchange during exercise.
TL;DR: The I-min incremental work rate test is associated with changes in gas exchange which can be used as sensitive on-line indicators of the AT, thus bypassing the need for measuring arterial lactate or acid-base parameters to indicate anaerobiosis.
Book
Numerical Methods for Scientists and Engineers
TL;DR: This inexpensive paperback edition of a groundbreaking classic is unique in its emphasis on the frequency approach and its use in the solution of problems.
Journal ArticleDOI
Numerical Methods for Scientists and Engineers.
Book
Principles of biochemistry
TL;DR: The principles of biochemistry as discussed by the authors, a.k.a. Principles of Biochemistry (PBI), were used in the development of the biochemistry of the human body.