A review of MRI findings in schizophrenia
TLDR
The 193 peer reviewed MRI studies reported in the current review span the period from 1988 to August, 2000 and have led to more definitive findings of brain abnormalities in schizophrenia than any other time period in the history of schizophrenia research.About:
This article is published in Schizophrenia Research.The article was published on 2001-04-15 and is currently open access. It has received 2298 citations till now. The article focuses on the topics: Superior temporal gyrus & Schizophrenia.read more
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Dynamic mapping of human cortical development during childhood through early adulthood
Nitin Gogtay,Jay N. Giedd,Leslie Lusk,Kiralee M. Hayashi,Deanna Greenstein,A. Catherine Vaituzis,Tom F. Nugent,David H. Herman,Liv S. Clasen,Arthur W. Toga,Judith L. Rapoport,Paul M. Thompson +11 more
TL;DR: The dynamic anatomical sequence of human cortical gray matter development between the age of 4-21 years using quantitative four-dimensional maps and time-lapse sequences reveals that higher-order association cortices mature only after lower-order somatosensory and visual cortices are developed.
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Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence.
TL;DR: This review critically summarizes the neuropathology and genetics of schizophrenia, the relationship between them, and speculates on their functional convergence via an influence upon synaptic plasticity and the development and stabilization of cortical microcircuitry.
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Abnormal neural oscillations and synchrony in schizophrenia
TL;DR: Dysfunctional oscillations may arise owing to anomalies in the brain's rhythm-generating networks of GABA (γ-aminobutyric acid) interneurons and in cortico-cortical connections.
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N-Acetylaspartate in the CNS: From neurodiagnostics to neurobiology
John R. Moffett,Brian D. Ross,Peethambaran Arun,Chikkathur N. Madhavarao,Aryan M.A. Namboodiri +4 more
TL;DR: Evidence suggests that NAA is a direct precursor for the enzymatic synthesis of the neuron specific dipeptides N-acetylaspartylglutamate, the most concentrated neuropeptide in the human brain, and it is proposed that N AA may also be involved in brain nitrogen balance.
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Regional Deficits in Brain Volume in Schizophrenia: A Meta-Analysis of Voxel-Based Morphometry Studies
TL;DR: Voxel-based morphometry can be used as an exploratory whole-brain approach to identify abnormal brain regions in schizophrenia, which should then be validated by using region-of-interest analyses.
References
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Neurogenesis in the adult human hippocampus
Peter S. Eriksson,Ekaterina Perfilieva,Thomas Björk-Eriksson,Ann Marie Alborn,Claes Nordborg,Daniel A. Peterson,Fred H. Gage +6 more
TL;DR: It is demonstrated that new neurons, as defined by these markers, are generated from dividing progenitor cells in the dentate gyrus of adult humans, indicating that the human hippocampus retains its ability to generate neurons throughout life.
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Memory and the hippocampus: A synthesis from findings with rats, monkeys, and humans.
TL;DR: The role of the hippocampus is considered, which is needed temporarily to bind together distributed sites in neocortex that together represent a whole memory.
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Oxidative stress, glutamate, and neurodegenerative disorders
TL;DR: Two broad mechanisms--oxidative stress and excessive activation of glutamate receptors--are converging and represent sequential as well as interacting processes that provide a final common pathway for cell vulnerability in the brain.
Book
Dementia Praecox or the Group of Schizophrenias
TL;DR: It's coming again, the new collection that this site has; the favorite dementia praecox or the group of schizophrenias monograph series on schizophrenia no 1 book is offered today.
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MR imaging of intravoxel incoherent motions: application to diffusion and perfusion in neurologic disorders.
TL;DR: A magnetic resonance (MR) method to image intravoxel incoherent motions (IVIMs) by using appropriate gradient pulses and nonuniform slow flow of cerebrospinal fluid appeared as a useful feature on IVIM images.