Amniotic fluid: not just fetal urine anymore.
TLDR
Current understanding of the origin and circulation of AF and its nutritive, protective, and diagnostic functions are reviewed and future directions for AF research are discussed.Abstract:
Amniotic fluid (AF) is a complex substance essential to fetal well-being. This article reviews recent discoveries and the current understanding of the origin and circulation of AF and its nutritive, protective, and diagnostic functions. Future directions for AF research are also discussed.read more
Citations
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Human Milk for the Premature Infant
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A global assessment of phthalates burden and related links to health effects.
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TL;DR: The aim of this review is to summarize the current state of knowledge on the toxicity that phthalates pose in humans based on human biomonitoring studies conducted over the last decade.
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Protecting the Newborn and Young Infant from Infectious Diseases: Lessons from Immune Ontogeny
TL;DR: How plasticity, i.e. the capacity to adapt to demands encountered in early life, also provides the potential to leverage protection of the young against infection and disease through a number of interventions is discussed.
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Prenatal exposure to environmental phenols: concentrations in amniotic fluid and variability in urinary concentrations during pregnancy.
Claire Philippat,Mary S. Wolff,Antonia M. Calafat,Xiaoyun Ye,Rebecca Bausell,Molly Meadows,Joanne Stone,Rémy Slama,Stephanie M. Engel +8 more
TL;DR: Although a single sample may provide a reasonable estimate of exposure for some phenols, collecting multiple urine samples during pregnancy is an option to reduce exposure measurement error in studies regarding the effects of phenol prenatal exposure on health.
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Human fetal dendritic cells promote prenatal T-cell immune suppression through arginase-2
Naomi McGovern,Amanda Shin,Amanda Shin,Gillian Low,Donovan Low,Kaibo Duan,Leong Jing Yao,Rasha Msallam,Ivy Low,Nurhidaya Binte Shadan,Hermi Sumatoh,Erin Soon,Josephine Lum,Esther Wing Hei Mok,Sandra Hubert,Peter See,Edwin Huang Kunxiang,Yie Hou Lee,Yie Hou Lee,Baptiste Janela,Mahesh Choolani,Citra Nurfarah Zaini Mattar,Yiping Fan,Yiping Fan,Tony Kiat Hon Lim,Dedrick Kok Hong Chan,Ker-Kan Tan,Ker-Kan Tan,John Kit Chung Tam,Christopher Schuster,Adelheid Elbe-Bürger,Xiao-Nong Wang,Venetia Bigley,Matthew Collin,Muzlifah Haniffa,Andreas Schlitzer,Andreas Schlitzer,Andreas Schlitzer,Michael Poidinger,Salvatore Albani,Anis Larbi,Evan W. Newell,Jerry Kok Yen Chan,Florent Ginhoux +43 more
TL;DR: The results reveal a previously unappreciated role of dendritic cells within the developing fetus and indicate that they mediate homeostatic immune-suppressive responses during gestation.
References
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Amniotic fluid as a novel source of mesenchymal stem cells for therapeutic transplantation
Pieternella S. in `t Anker,Sicco A. Scherjon,Carin Kleijburg-van der Keur,Willy A. Noort,Frans H.J. Claas,Roelof Willemze,Willem E. Fibbe,Humphrey H.H. Kanhai +7 more
TL;DR: This work has shown that human fetal lung–derived MSCs enhance the engraftment of human umbilical cord blood (UCB)–derived CD34+ hematopoietic cells in UCB-derived patients.
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Neonatal necrotizing enterocolitis: clinical considerations and pathogenetic concepts.
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TL;DR: The initial event in experimental models of NEC is probably polymorphonuclear leukocyte activation and adhesion to venules in the intestine, which initiates a local inflammatory reaction involving proinflammatory mediators including TNF, complement, prostaglandins, and leukotriene C4.
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Management of rhesus alloimmunization in pregnancy.
TL;DR: The rarity of rhesus immune globulin in pregnancy warrants consideration of consultation with or referral to a maternal–fetal medicine specialist with experience in the monitoring and treatment of patients with red cell alloimmunization in pregnancy.
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Normal amniotic fluid volume changes throughout pregnancy.
Robert A. Brace,Edward J. Wolf +1 more
TL;DR: It was found that after log transformation, amniotic fluid volume had a uniform variability over 8 to 43 weeks' gestation, and the 95% confidence interval covered the range of 1/2.57 to 2.57 times the mean volume at any given gestational age.
Journal ArticleDOI
Cells, matrix, growth factors, and the surgeon. The biology of scarless fetal wound repair.
N S Adzick,H P Lorenz +1 more
TL;DR: Based on the scarless fetal wound repair model, a number of ways in which the matrix and cellular response of the healing adult wound might be manipulated to reduce scarring are reviewed.