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Journal ArticleDOI

Conducting polypyrrole in tissue engineering applications

TLDR
Although some challenges and unanswered problems still remain, PPy as novel biomaterial has promoted the development tissue engineering for its clinical application in the future.
Abstract
Polypyrrole (PPy), the earliest prepared conducting polymer, has good biocompatibility, easy synthesis and flexibility in processing. Compared with metal and inorganic materials, doped PPy has better mechanical match with live tissue, resulting in its many applications in biomedical field. This mini-review presents some information on specific PPy properties for tissue engineering applications, including its synthesis, doping, bio-modification. Although some challenges and unanswered problems still remain, PPy as novel biomaterial has promoted the development tissue engineering for its clinical application in the future.

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Journal ArticleDOI

Electrically conductive polymers and composites for biomedical applications

TL;DR: A review of the recent investigations conducted in the development of conductive polymer composites focussing on the methods of their preparation, underlying concepts of their conductivity and the ways to tailor their properties is also discussed as mentioned in this paper.

Electrically conducting polymers cannoninvasively control the shapeandgrowth ofmammalian cells

TL;DR: The data suggest that electrically conducting polymers may represent a type of culture substrate which could provide a noninvasive means to control the shape and function of adherent cells, independent of any medium alteration.
Journal ArticleDOI

Conductive and Tough Hydrogels Based on Biopolymer Molecular Templates for Controlling in Situ Formation of Polypyrrole Nanorods

TL;DR: A new strategy for the fabrication of tough CHs with excellent conductivity, superior mechanical properties, and good biocompatibility is reported by using chitosan framework as molecular templates for controlling conducting polypyrrole (PPy) nanorods in situ formation inside the hydrogel networks.
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Hierarchically designed bone scaffolds: From internal cues to external stimuli

TL;DR: This review summarizes recent advances within the field in utilizing three critical elements - cells, scaffolds, and bioactive factors - to recapitulate the bone tissue microenvironment, inducing the formation of new bone.
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Application of conducting polymers to wound care and skin tissue engineering: A review.

TL;DR: Results indicated that PANI and PPy, two CPs that have been most extensively studied across a range of applications, including biological, were also most frequently used in wound dressings and hydrogels, and P Py was most commonly applied to skin tissue scaffolds.
References
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Book

Handbook of conducting polymers

TL;DR: In this paper, the authors presented the theory and properties of conjugated polymers, including transport, optical, and self-assembly properties of poly(3,4-Ethylenedioxythiophene)-polymers.
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Synthesis of electrically conducting organic polymers: halogen derivatives of polyacetylene, (CH)x

TL;DR: When silvery films of the semiconducting polymer, trans polyacetylene, (CH)x, are exposed to chlorine, bromine, or iodine vapour, uptake of halogen occurs, and the conductivity increases markedly (over seven orders of magnitude in the case of iodine) to give silvery or silvery-black films, some of which have a remarkably high conductivity at room temperature.
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Semiconducting and Metallic Polymers: The Fourth Generation of Polymeric Materials (Nobel Lecture).

TL;DR: When asked to explain the importance of the discovery of conducting polymers, I offer two basic answers: first they did not (could not?) exist, and second, that they offer a unique combination of properties not available from any other known materials.
Journal ArticleDOI

Conducting polymers in biomedical engineering

TL;DR: Although there remain many unanswered questions, particularly regarding the mechanisms by which electrical conduction through CPs affects cells, there is already compelling evidence to demonstrate the significant impact that CPs are starting to make in the biomedical field.
Journal ArticleDOI

Stimulation of neurite outgrowth using an electrically conducting polymer

TL;DR: The electrically conductive polymer--oxidized polypyrrole (PP)--has been evaluated for use as a substrate to enhance nerve cell interactions in culture as a first step toward potentially using such polymers to stimulate in vivo nerve regeneration.
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