Journal ArticleDOI
Data quality and quality control of a population-based cancer registry. Experience in Finland.
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TLDR
Active research policy and ambitious, research-oriented staff with competence in medicine, biostatistics and computer science are essential in terms of maintaining good data quality.Abstract:
Cancer registries should pay great attention to the quality of their data, both in terms of completeness (all cancer patients in the population are registered) and accuracy (data on individual cancer patients must be correct). In addition to technical measures in the data processing, different types of checks and comparisons should be routine practice. Active research policy and ambitious, research-oriented staff with competence in medicine, biostatistics and computer science are essential in terms of maintaining good data quality.read more
Citations
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Journal ArticleDOI
Environmental and Heritable Factors in the Causation of Cancer — Analyses of Cohorts of Twins from Sweden, Denmark, and Finland
Paul Lichtenstein,Niels V. Holm,Pia K. Verkasalo,Anastasia Iliadou,Jaakko Kaprio,Jaakko Kaprio,Markku Koskenvuo,Markku Koskenvuo,Eero Pukkala,Axel Skytthe,Kari Hemminki +10 more
TL;DR: Inherited genetic factors make a minor contribution to susceptibility to most types of neoplasms, which indicates that the environment has the principal role in causing sporadic cancer.
Journal ArticleDOI
Flavonoid intake and risk of chronic diseases
Paul Knekt,Jorma Kumpulainen,Ritva Järvinen,Harri Rissanen,Markku Heliövaara,Antti Reunanen,Timo Hakulinen,Arpo Aromaa +7 more
TL;DR: The risk of some chronic diseases may be lower at higher dietary flavonoid intakes, and a trend toward a reduction in risk of type 2 diabetes was associated with higher quercetin intakes.
Journal ArticleDOI
Cancer risk in mutation carriers of DNA-mismatch-repair genes.
M. Aarnio,Risto Sankila,Eero Pukkala,Reijo Salovaara,Lauri A. Aaltonen,A de la Chapelle,Päivi Peltomäki,Jukka-Pekka Mecklin,Heikki Järvinen +8 more
TL;DR: The tumour spectrum associated with germline mutations of DNA‐mismatch‐repair genes involves 8 or more organ sites, suggesting a need to develop methods to screen for extra‐colonic cancer also.
Journal ArticleDOI
Incidence of Hereditary Nonpolyposis Colorectal Cancer and the Feasibility of Molecular Screening for the Disease
Lauri A. Aaltonen,Reijo Salovaara,P. Kristo,Federico Canzian,Akseli Hemminki,Päivi Peltomäki,Robert B. Chadwick,H Kääriäinen,Matti Eskelinen,H Järvinen,Mecklin Jp,A. de la Chapelle +11 more
TL;DR: Tumor specimens obtained from 509 consecutive patients with colorectal adenocarcinomas were screened for DNA replication errors and germ-line mutations of the mismatch-repair genes MLH1 and MSH2, finding at least 2 percent had hereditary nonpolyposis coloreCTal cancer.
Journal ArticleDOI
The completeness of the Swedish Cancer Register: a sample survey for year 1998.
TL;DR: The overall completeness of the SCR is high and comparable to other high quality registers in Northern Europe, and the degree of underreporting is site specific, increases with age, and does not seem to be random.
References
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Journal ArticleDOI
Completeness of the Swedish Cancer Register Non-Notified Cancer Cases Recorded on Death Certificates in 1978
B Mattsson,A Wallgren +1 more
TL;DR: Of the death certificates issued in Sweden in 1978 and stating cancer as the underlying or contributory cause of death, 1634 cases were unrecorded in the national cancer register, which represents a deficit of 4.5 per cent calculated on cancer deaths in 1978.
Journal Article
Completeness and accuracy of registration of colorectal cancer in Finland.
Kyllönen Le,Teppo L,Lehtonen M +2 more
TL;DR: Data from the Finnish Cancer Registry notifications of colorectal cancer diagnosed in Finland in 1975 were compared against original patient records, and hospital archives were searched for unregistered cases.
Journal Article
Reliability of histopathologic diagnosis of malignant lymphoma.
M Hakama,K Franssila,E Saxén +2 more
Book ChapterDOI
Histological Classification and its Implications in the Utility of Registry Data in Epidemiological Studies
TL;DR: The value of cancer registry data in epidemiological studies concerned with cancer is dependent upon the reliability and comparability of the data used, and it is necessary for the material to have been processed with reference to uniform classification and coding systems.