Open AccessJournal Article
Determination of creatine and creatinine
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This article is published in Nihon rinsho. Japanese journal of clinical medicine.The article was published on 1976-01-01 and is currently open access. It has received 9 citations till now. The article focuses on the topics: Creatinine & Creatine.read more
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Long-Term Correction of Ornithine Transcarbamylase Deficiency by WPRE-Mediated Overexpression Using a Helper-Dependent Adenovirus
Asad Mian,W. Michael McCormack,Viraj Mane,Soledad Kleppe,Philip Ng,Milton J. Finegold,William E. O'Brien,John R. Rodgers,Arthur L. Beaudet,Brendan Lee +9 more
TL;DR: Post-transcriptional overexpression in the context of the less immunogenic helper-dependent adenoviral vector achieved metabolic correction of adult OTC-deficient mice for >6 months, and represents an important approach for treating human inborn errors of hepatocyte metabolism like the UCDs that require high-level transduction and gene expression for clinical correction.
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Alterations of serum and urinary carnitine profiles in cancer patients: hypothesis of possible significance.
TL;DR: The increased clearance of acylcarnitine and excretion of large amounts of AIAC are proposed to be a response to chemotherapy and represent a loss of energy to the cancer patient.
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Choline supplementation reduces urinary carnitine excretion in humans.
Wanda L Dodson,Dileep S. Sachan +1 more
TL;DR: Choline, but not pantothenate, supplementation significantly decreased urinary carnitine excretion, renal clearance, and fractional clearance of NEC, and it is concluded that supplementary choline maintained serum carnItine concentrations by conserving urinary carn itine.
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Effects of carnitine coingested caffeine on carnitine metabolism and endurance capacity in athletes.
TL;DR: Carnitine ingestion could promote fat oxidation, resulting in higher endurance performance in athletes, and especially these ergogenic effects of carnitine coingested with caffeine may be greater than those of carn itine alone.
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Basal urinary zinc/creatinine ratio as an indicator of dietary zinc intake in healthy adult women.
TL;DR: The results showed that the basal urinary Zn/Creat ratio could be a useful indicator of dietary Zn intake in healthy adult women.