Journal ArticleDOI
Effects of dietary nitrate on oxygen cost during exercise
TLDR
This study investigated if dietary nitrate had any effect on metabolic and circulatory parameters during exercise and found that it did not.Abstract:
AIM: Nitric oxide (NO), synthesized from l-arginine by NO synthases, plays a role in adaptation to physical exercise by modulating blood flow, muscular contraction and glucose uptake and in the con read more
Citations
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Journal ArticleDOI
The nitrate–nitrite–nitric oxide pathway in physiology and therapeutics
TL;DR: This Review discusses the emerging important biological functions of the nitrate–nitrite–NO pathway, and highlights studies that implicate the therapeutic potential of nitrate and nitrite in conditions such as myocardial infarction, stroke, systemic and pulmonary hypertension, and gastric ulceration.
Journal ArticleDOI
Food sources of nitrates and nitrites: the physiologic context for potential health benefits
TL;DR: Data call into question the rationale for recommendations to limit nitrate and nitrite consumption from plant foods; a comprehensive reevaluation of the health effects of food sources of nitrates and nitrites is appropriate.
Journal ArticleDOI
Dietary nitrate supplementation reduces the O2 cost of low-intensity exercise and enhances tolerance to high-intensity exercise in humans
Stephen J. Bailey,Paul G. Winyard,Anni Vanhatalo,Jamie R. Blackwell,Fred J. DiMenna,Daryl P. Wilkerson,Joanna M. Tarr,Nigel Benjamin,Andrew M. Jones +8 more
TL;DR: The reduced O2 cost of exercise following increased dietary nitrate intake has important implications for the understanding of the factors that regulate mitochondrial respiration and muscle contractile energetics in humans.
Journal ArticleDOI
Dietary inorganic nitrate improves mitochondrial efficiency in humans.
Filip J. Larsen,Tomas A. Schiffer,Sara Borniquel,Kent Sahlin,Björn Ekblom,Jon O. Lundberg,Eddie Weitzberg +6 more
TL;DR: It is concluded that dietary nitrate has profound effects on basal mitochondrial function and whole-body oxygen consumption in healthy volunteers and may have implications for exercise physiology- and lifestyle-related disorders that involve dysfunctional mitochondria.
Journal ArticleDOI
Dietary nitrate supplementation enhances muscle contractile efficiency during knee-extensor exercise in humans
Stephen J. Bailey,Jonathan Fulford,Anni Vanhatalo,Paul G. Winyard,Jamie R. Blackwell,Fred J. DiMenna,Daryl P. Wilkerson,Nigel Benjamin,Andrew M. Jones +8 more
TL;DR: The reduced O(2) cost of exercise following dietary NO(3)(-) supplementation appears to be due to a reduced ATP cost of muscle force production.
References
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Book
Textbook of Work Physiology
Per-Olof Åstrand,Kåre Rodahl +1 more
TL;DR: Find loads of the textbook of work physiology book catalogues in this site as the choice of you visiting this page.
Journal ArticleDOI
Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation.
Kenyatta Cosby,Kristine S. Partovi,Jack H. Crawford,Rakesh P. Patel,Christopher D. Reiter,Sabrina Martyr,Benjamin K. Yang,Myron A. Waclawiw,Gloria Zalos,Xiuli Xu,Kris T. Huang,Howard Shields,Daniel B. Kim-Shapiro,Alan N. Schechter,Richard O. Cannon,Mark T. Gladwin +15 more
TL;DR: It is suggested that nitrite represents a major bioavailable pool of NO, and a new physiological function for hemoglobin as a nitrite reductase is described, potentially contributing to hypoxic vasodilation.
Journal ArticleDOI
Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide. Implications for neurodegenerative diseases.
M. W. J. Cleeter,JM Cooper,Victor M. Darley-Usmar,Salvador Moncada,Anthony H.V. Schapira,Anthony H.V. Schapira +5 more
TL;DR: Results indicate that nitric oxide is capable of rapidly and reversibly inhibiting the mitochondrial respiratory chain and may be implicated in the cytotoxic effects of Nitric oxide in the CNS and other tissues.
Journal ArticleDOI
Physiology of Nitric Oxide in Skeletal Muscle
TL;DR: These studies provide new insights into fundamental aspects of muscle physiology, cell biology, ion channel physiology, calcium homeostasis, signal transduction, and the biochemistry of redox-related systems.