Journal ArticleDOI
Epidemiology of Mucormycosis in India
TLDR
The spectrum of etiological agents causing mucormycosis is unique as Apophysomyces elegans is the second most common pathogen after Rhizopus oryzae and many new agents are identified causing the disease.Abstract:
Mucormycosis is an emerging healthcare problem in the Indian population. The epidemiology of the disease is distinct with very high incidence among uncontrolled diabetics. The patients present commonly as rhino-orbito-cerebral mucormycosis, which is easy to diagnose. But, the mortality rate remains high (nearly 50 %), as the patients attend the healthcare facility late in the course of the disease after extensive spread of infection. Isolated renal mucormycosis in young apparently healthy individuals is a new form of the disease. The spectrum of etiological agents causing mucormycosis is also unique as Apophysomyces elegans is the second most common pathogen after Rhizopus oryzae. Many new agents are identified causing the disease.read more
Citations
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Journal ArticleDOI
Global Epidemiology of Mucormycosis
TL;DR: With the change in epidemiology of mucormycosis country-wise studies are warranted to estimate disease burden in different risk groups, analyse the clinical disease pattern and identify the new etiological agents.
Journal ArticleDOI
Epidemiology of Mucormycosis in India.
TL;DR: The exact incidence of mucormycosis in India is unknown due to the lack of population-based studies as discussed by the authors, however, the estimated prevalence of the disease is around 70 times higher in India than that in global data.
Journal ArticleDOI
Mucormycosis in India: unique features.
TL;DR: This review focuses on distinct features of mucormycosis observed in India, where Rhino‐orbito‐cerebral presentation associated with uncontrolled diabetes is the predominant characteristic and isolated renal mucormYcosis has emerged as a new clinical entity.
Journal ArticleDOI
COVID-19-associated fungal infections
Martin Hoenigl,Danila Seidel,Rosanne Sprute,Cristina Cunha,Matteo Oliverio,Gustavo H. Goldman,Ashraf S. Ibrahim,Agostinho Carvalho +7 more
TL;DR: In this article , the authors reviewed the incidence of COVID-19-associated invasive fungal infections caused by these fungi in low-, middle- and high-income countries, evaluating the epidemiology, clinical risk factors, predisposing features of the host environment and immunological mechanisms that underlie the pathogenesis of these co-infections, set the scene for future research and development of clinical guidance.
Journal ArticleDOI
Mucormycosis in Iran: a systematic review
TL;DR: Owing to the high mortality rate of advanced mucormycosis, early diagnosis and treatment may significantly improve survival rates, and increased monitoring and awareness of this life‐threatening disease is critical.
References
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Book
Principles and Practice of Infectious Diseases
TL;DR: This updated and expanded edition now offers 297 chapters that cover the basic principles of diagnosis and management, major clinical syndromes, all important pathogenic microbes and the diseases they cause, plus a number of specialised topics useful to the practitioner.
Journal ArticleDOI
Epidemiology and Outcome of Zygomycosis: A Review of 929 Reported Cases
Maureen Roden,Theoklis E. Zaoutis,Wendy Buchanan,Tena A. Knudsen,Tatyana A. Sarkisova,Robert L. Schaufele,Michael Sein,Tin Sein,Christine C. Chiou,Jaclyn H. Chu,Dimitrios P. Kontoyiannis,Thomas J. Walsh +11 more
TL;DR: Outcome from zygomycosis varies as a function of the underlying condition, site of infection, and use of antifungal therapy; however, infection due to Cunninghamella species and dissemination were independently associated with increased rates of death.
Journal ArticleDOI
Epidemiology and Clinical Manifestations of Mucormycosis
George Petrikkos,Anna Skiada,Olivier Lortholary,Emmanuel Roilides,Thomas J. Walsh,Dimitrios P. Kontoyiannis +5 more
TL;DR: The emerging epidemiology and the clinical manifestations of mucormycosis are described and this disease is increasingly recognized in recently developed countries, such as India, mainly in patients with uncontrolled diabetes or trauma.
Journal ArticleDOI
Zygomycosis in a Tertiary-Care Cancer Center in the Era of Aspergillus-Active Antifungal Therapy: A Case-Control Observational Study of 27 Recent Cases
Dimitrios P. Kontoyiannis,Michail S. Lionakis,Russell E. Lewis,Russell E. Lewis,Georgios Chamilos,Mimi Healy,Cheryl Perego,Amar Safdar,Hagop M. Kantarjian,Richard E. Champlin,Thomas J. Walsh,Issam I Raad +11 more
TL;DR: Zygomycosis should be considered in immunosuppressed patients who develop sinusitis while receiving VRC prophylaxis, especially those with diabetes and malnutrition.
Journal ArticleDOI
Zygomycosis in Europe: analysis of 230 cases accrued by the registry of the European Confederation of Medical Mycology (ECMM) Working Group on Zygomycosis between 2005 and 2007
Anna Skiada,Livio Pagano,Andreas H. Groll,Stephan Zimmerli,Bertrand Dupont,Katrien Lagrou,Cornelia Lass-Flörl,Emilio Bouza,Nikolay Klimko,Peter Gaustad,Malcolm Richardson,Petr Hamal,Murat Akova,Jacques F. Meis,J. L. Rodriguez-Tudela,Emmanuel Roilides,A. Mitrousia-Ziouva,George Petrikkos +17 more
TL;DR: Administration of amphotericin B and surgery, where feasible, significantly improve survival and the most common manifestations of zygomycosis were pulmonary, rhinocerebral and soft tissue.