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Gastrointestinal health and function in weaned pigs: a review of feeding strategies to control post‐weaning diarrhoea without using in‐feed antimicrobial compounds

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TLDR
Some of nutritional strategies known to improve structure and function of gastrointestinal tract and (or) promote post-weaning growth with special emphasis on probiotics, prebiotics, organic acids, trace minerals and dietary protein source and level are focused on.
Abstract
For the last several decades, antimicrobial compounds have been used to promote piglet growth at weaning through the prevention of subclinical and clinical disease. There are, however, increasing concerns in relation to the development of antibiotic-resistant bacterial strains and the potential of these and associated resistance genes to impact on human health. As a consequence, European Union (EU) banned the use of antibiotics as growth promoters in swine and livestock production on 1 January 2006. Furthermore, minerals such as zinc (Zn) and copper (Cu) are not feasible alternatives/replacements to antibiotics because their excretion is a possible threat to the environment. Consequently, there is a need to develop feeding programs to serve as a means for controlling problems associated with the weaning transition without using antimicrobial compounds. This review, therefore, is focused on some of nutritional strategies that are known to improve structure and function of gastrointestinal tract and (or) promote post-weaning growth with special emphasis on probiotics, prebiotics, organic acids, trace minerals and dietary protein source and level.

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Journal ArticleDOI

Gut Microbiota Dysbiosis in Postweaning Piglets: Understanding the Keys to Health

TL;DR: Nonantimicrobial alternatives, such as zinc oxide, essential oils, and prebiotics or probiotics, which are currently evaluated to restore intestinal balance and allow a better management of the crucial weaning transition are focused on.
Journal ArticleDOI

Alternatives to antibiotics for maximizing growth performance and feed efficiency in poultry: a review.

TL;DR: Optimal combinations of various alternatives coupled with good management and husbandry practices will be the key to maximize performance and maintain animal productivity, while the ultimate goal of reducing antibiotic use in the animal industry is moved forward.
Journal ArticleDOI

Treatment, promotion, commotion: antibiotic alternatives in food-producing animals

TL;DR: A fundamental understanding of how antibiotics improve feed efficiency is lacking, and an individual alternative is unlikely to embody all of the performance-enhancing functions of antibiotics.
Journal ArticleDOI

Post weaning diarrhea in pigs: risk factors and non‑colistin‑based control strategies

TL;DR: To overcome the economic losses, which would result from the restriction of use of colistin, especially for prophylactic purposes in PWD control, it is believed that an understanding of the factors contributing to the development of this disease and the putting in place of practical alternative strategies is crucial.
Journal ArticleDOI

The role of added feed enzymes in promoting gut health in swine and poultry.

TL;DR: In this paper, the authors investigated the impact of added feed enzymes (FE) on the microbiome of the gastrointestinal tract (GIT) and found that FE can make an impact on GIT microbial ecology by reducing undigested substrates and anti-nutritive factors.
References
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Journal ArticleDOI

Dietary Modulation of the Human Colonic Microbiota: Introducing the Concept of Prebiotics

TL;DR: By combining the rationale of pro- and prebiotics, the concept of synbiotics is proposed to characterize some colonic foods with interesting nutritional properties that make these compounds candidates for classification as health-enhancing functional food ingredients.
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Dietary modulation of the human colonic microbiota: updating the concept of prebiotics

TL;DR: The future use of prebiotics may allow species-level changes in the microbiota, an extrapolation into genera other than the bifidobacteria and lactobacilli, and allow preferential use in disease-prone areas of the body.
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Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. V. Unitarian Theory of the origin of the four epithelial cell types.

TL;DR: It is concluded that crypt-base columnar cells transform into cells of these four types and, therefore, behave as the stem cells of the epithelium and support the Unitarian Theory of epithelial cell formation in the small intestine.
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Probiotics, prebiotics, and synbiotics—approaching a definition

TL;DR: The probiotic concept is confined to effects exerted by viable microorganisms but is applicable independent of the site of action and route of administration, and may include sites such as the oral cavity, the intestine, the vagina, and the skin.
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Prebiotics: the concept revisited.

TL;DR: A prebiotic is a selectively fermented ingredient that allows specific changes, both in the composition and/or activity in the gastrointestinal microflora that confers benefits upon host well-being and health and the "dose argument" is not supported by the scientific data: it is misleading for consumers and should not be allowed.
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