Lower risk of stent thrombosis and restenosis with unrestricted use of onew-generation' drug-eluting stents: a report from the nationwide Swedish Coronary Angiography and Angioplasty Registry (SCAAR)
Giovanna Sarno,Bo Lagerqvist,Ole Fröbert,Johan Nilsson,Göran K. Olivecrona,Elmir Omerovic,Nawzad Saleh,Dimitris Venetzanos,Stefan James +8 more
TLDR
Percutaneous coronary intervention with 'new-generation' drug-eluting stents (n-DES) to 'older generation' DES (o-DES), and bare-metal stent implantations in a real-world population is associated with a 38% lower risk of clinically meaningful restenosis, a 43% lowerrisk of definite ST, and a 23% lower chance of death compared with o-DES in this observational study from a large real- world population.Abstract:
To compare the long-term outcome after percutaneous coronary intervention with onew-generation' drug-eluting stents (n-DES) to oolder generation' DES (o-DES), and bare-metal stents (BMS) in a real- ...read more
Citations
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2013 ESC guidelines on the management of stable coronary artery disease: the Task Force on the management of stable coronary artery disease of the European Society of Cardiology.
Gilles Montalescot,Udo Sechtem,Stephan Achenbach,Felicita Andreotti,Chris Arden,Andrzej Budaj,Raffaele Bugiardini,Filippo Crea,Thomas Cuisset,Carlo Di Mario,J. Rafael Ferreira,Bernard J. Gersh,Anselm K. Gitt,Jean-Sébastien Hulot,Nikolaus Marx,Lionel H. Opie,Matthias Pfisterer,Eva Prescott,Frank Ruschitzka,Manel Sabaté,Roxy Senior,David P. Taggart,Ernst E. van der Wall,Christiaan J. Vrints,José Luis Zamorano,Helmut Baumgartner,Jeroen J. Bax,Héctor Bueno,Veronica Dean,Christi Deaton,Çetin Erol,Robert Fagard,Roberto Ferrari,David Hasdai,Arno W. Hoes,Paulus Kirchhof,Juhani Knuuti,Philippe Kolh,Patrizio Lancellotti,Aleš Linhart,Petros Nihoyannopoulos,Massimo F Piepoli,Piotr Ponikowski,Per Anton Sirnes,Juan Tamargo,Michal Tendera,Adam Torbicki,William Wijns,Stephan Windecker,Marco Valgimigli,Marc J. Claeys,Norbert Donner-Banzhoff,Herbert Frank,Christian Funck-Brentano,Oliver Gaemperli,José Ramón González-Juanatey,Michalis Hamilos,Steen Husted,Stefan James,Kari Kervinen,Steen Dalby Kristensen,Aldo P. Maggioni,Axel R. Pries,Francesco Romeo,Lars Rydén,Maarten L. Simoons,Ph. Gabriel Steg,Adam Timmis,Aylin Yildirir +68 more
TL;DR: The If Inhibitor Ivabradine in Patients With Coronary Artery Disease and Left Ventricular Dysfunction is evaluated as well as patients with Diabetes mellitus for Optimal management of Multivessel disease.
Journal ArticleDOI
2019 ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD
Francesco Cosentino,Peter J. Grant,Victor Aboyans,Clifford J Bailey,Antonio Ceriello,Victoria Delgado,Massimo Federici,Gerasimos Filippatos,Diederick E. Grobbee,Tina Birgitte Hansen,Heikki V. Huikuri,I. Johansson,Peter Jüni,Maddalena Lettino,Nikolaus Marx,Linda Mellbin,Carl J. Östgren,Bianca Rocca,Marco Roffi,Naveed Sattar,Petar M. Seferović,Miguel Sousa-Uva,Paul Valensi,David C Wheeler +23 more
TL;DR: The second iteration of the European Society of Cardiology (ESC) and European Association for the Study of Diabetes (EASD) joining forces to write guidelines on the management of diabetes mellitus (DM), pre-diabetes, and cardiovascular disease (CVD), designed to assist clinicians and other healthcare workers to make evidence-based management decisions.
Journal ArticleDOI
ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD: the Task Force on diabetes, pre-diabetes, and cardiovascular diseases of the European Society of Cardiology (ESC) and developed in collaboration with the European Association for the Study of Diabetes (EASD)
Journal ArticleDOI
Drug-Eluting or Bare-Metal Stents for Coronary Artery Disease
Kaare H. Bønaa,Jan Mannsverk,Rune Wiseth,Lars Aaberge,Yngvar Myreng,Ottar Nygård,Dennis W.T. Nilsen,Nils-Einar Kløw,Michael Uchto,Thor Trovik,Bjørn Bendz,Sindre Stavnes,Reidar Bjørnerheim,A.I Larsen,Morten Slette,Terje K. Steigen,Ole J Jakobsen,Øyvind Bleie,Eigil Fossum,Tove Aminda Hanssen,Øystein Dahl-Eriksen,Inger Njølstad,Knut Rasmussen,Tom Wilsgaard,Jan Erik Nordrehaug,Norstent Investigators +25 more
TL;DR: In patients undergoing PCI, there were no significant differences between those receiving drug-eluting stents and those receiving bare-metal stents in the composite outcome of death from any cause and nonfatal spontaneous myocardial infarction.
Journal ArticleDOI
Outcomes 1 Year after Thrombus Aspiration for Myocardial Infarction
Bo Lagerqvist,Ole Fröbert,Göran K. Olivecrona,Thorarinn Gudnason,Michael Maeng,Patrik Alström,Jonas Andersson,Fredrik Calais,Jörg Carlsson,Olov Collste,Matthias Götberg,Peter Hårdhammar,Dan Ioanes,Anders Kallryd,Rickard Linder,Anders Lundin,Jacob Odenstedt,Elmir Omerovic,Verner Puskar,Tim Tödt,Eva Zelleroth,Ollie Östlund,Stefan James +22 more
TL;DR: Routine thrombus aspiration before PCI in patients with STEMI did not reduce the rate of death from any cause or the composite of deathFrom any cause, rehospitalization for myocardial infarction, or stent thrombosis at 1 year.
References
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Clinical End Points in Coronary Stent Trials A Case for Standardized Definitions
Donald E. Cutlip,Stephan Windecker,Roxana Mehran,Ashley B Boam,David J. Cohen,Gerrit-Anne van Es,P. Gabriel Steg,Marie-Angèle Morel,Laura Mauri,Pascal Vranckx,Eugene P. McFadden,Alexandra J. Lansky,Martial Hamon,Mitchell W. Krucoff,Patrick W. Serruys +14 more
TL;DR: Criteria for assessment of death, myocardial infarction, repeat revascularization, and stent thrombosis were developed and provide consistency across studies that can facilitate the evaluation of safety and effectiveness of these devices.
Journal ArticleDOI
Pathology of Drug-Eluting Stents in Humans: Delayed Healing and Late Thrombotic Risk
Michael Joner,Aloke V. Finn,Andrew Farb,Erik Mont,Frank D. Kolodgie,Elena Ladich,Robert Kutys,Kristi Skorija,Herman K. Gold,Renu Virmani +9 more
TL;DR: The Cypher and Taxus DES result in delayed arterial healing when compared with BMS of similar implant duration, and the cause of DES LST is multifactorial with delayed healing in combination with other clinical and procedural risk factors playing a role.
Journal ArticleDOI
Late thrombosis in drug-eluting coronary stents after discontinuation of antiplatelet therapy.
Eugene P. McFadden,Eugenio Stabile,Evelyn Regar,Edouard Cheneau,Andrew T.L. Ong,Tim Kinnaird,William O. Suddath,Neil J. Weissman,Rebecca Torguson,Kenneth M. Kent,A.D. Pichard,Lowell F. Satler,Ron Waksman,Patrick W. Serruys +13 more
TL;DR: Four cases of angiographically-confirmed stent thrombosis that occurred late after elective implantation of polymer-based paxlitaxel-eluting or sirolimus-eluted stents, and resulted in myocardial infarction are reported.
Journal ArticleDOI
Outcomes associated with drug-eluting and bare-metal stents: a collaborative network meta-analysis
Christoph Stettler,Christoph Stettler,Simon Wandel,Sabin Allemann,Adnan Kastrati,Marie Claude Morice,Albert Schömig,Matthias Pfisterer,Gregg W. Stone,Martin B. Leon,José Suárez de Lezo,Jean-Jacques Goy,Seung-Jung Park,Manel Sabaté,Maarten J. Suttorp,Henning Kelbæk,Christian Spaulding,Maurizio Menichelli,Paul Vermeersch,Maurits T. Dirksen,Pavel Cervinka,Anna Sonia Petronio,Alain J Nordmann,Peter Diem,Bernhard Meier,Marcel Zwahlen,Stephan Reichenbach,Sven Trelle,Stephan Windecker,Peter Jüni,Peter Jüni +30 more
TL;DR: A network meta-analysis with a mixed-treatment comparison method to combine direct within-trial comparisons between stents with indirect evidence from other trials while maintaining randomisation found sirolimus-eluting stents seem to be clinically better than bare-metal and paclitaxel-eluted stents.
Journal ArticleDOI
Pathological Correlates of Late Drug-Eluting Stent Thrombosis Strut Coverage as a Marker of Endothelialization
Aloke V. Finn,Michael Joner,Gaku Nakazawa,Frank D. Kolodgie,John B. Newell,Michael C. John,Herman K. Gold,Renu Virmani +7 more
TL;DR: Heterogeneity of healing is a common finding in drug-eluting stents with evidence of LST and demonstrates the importance of incomplete healing of the stented segment in the pathophysiology of L ST.