Nanomaterials for biosensing applications: a review
TLDR
This review summarizes in a non-exhaustive way the advantages of nanomaterials by focusing on nano-objects which provide further beneficial properties than “just” an enhanced surface area.Abstract:
A biosensor device is defined by its biological, or bioinspired receptor unit with unique specificities towards corresponding analytes. These analytes are often of biological origin like DNAs or proteins from the immune system (antibodies, antigens) of diseases or infections. Such analytes can also be simple molecules like glucose or pollutants when a biological receptor unit with particular specificity is available. One of many other challenges in biosensor development is the efficient signal capture of the biological recognition event (transduction). Such transducers translate the interaction of the analyte with the biological element into electrochemical, electrochemiluminescent, magnetic, gravimetric, or optical signals. In order to increase sensitivities and to lower detection limits down to even individual molecules, nanomaterials are promising candidates due to the possibility to immobilize an enhanced quantity of bioreceptor units at reduced volumes and even to act itself as transduction element. Among such nanomaterials, gold nanoparticles, semi-conductor quantum dots, polymer nanoparticles, carbon nanotubes, nanodiamonds, and graphene are intensively studied. Due to the vast evolution of this research field, this review summarizes in a non-exhaustive way the advantages of nanomaterials by focusing on nano-objects which provide further beneficial properties than “just” an enhanced surface area.read more
Citations
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Nanoparticles: Properties, applications and toxicities
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Nano based drug delivery systems: recent developments and future prospects
Jayanta Kumar Patra,Gitishree Das,Leonardo Fernandes Fraceto,Leonardo Fernandes Fraceto,Estefania Vangelie Ramos Campos,Estefania Vangelie Ramos Campos,Maria del Pilar Rodriguez-Torres,Laura Susana Acosta-Torres,Luis A. Diaz-Torres,Renato Grillo,Mallappa Kumara Swamy,Shivesh Sharma,Solomon Habtemariam,Han-Seung Shin +13 more
TL;DR: An updated summary of recent advances in the field of nanomedicines and nano based drug delivery systems through comprehensive scrutiny of the discovery and application of nanomaterials in improving both the efficacy of novel and old drugs and selective diagnosis through disease marker molecules is presented.
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Electrically-Transduced Chemical Sensors Based on Two-Dimensional Nanomaterials
TL;DR: Key advances in the application of 2D materials, from both a historical and analytical perspective, are summarized for four different groups of analytes: gases, volatile compounds, ions, and biomolecules.
(CdSe)ZnS Core−Shell Quantum Dots: Synthesis and Characterization of a Size Series of Highly Luminescent Nanocrystallites
Catherine J. Murphy,Tapan K. Sau,Anand M. Gole,Christopher J. Orendorff,Jinxin Gao,Linfeng Gou,Simona E. Hunyadi,Hannes C. Schniepp,Je-Luen Li,Michael J. McAllister,Hiroaki Sai,Margarita Herrera-Alonso,Douglas H. Adamson,Robert K. Prud'homme,Roberto Car,Dudley A. Saville,Ilhan A. Aksay,Prashant K. Jain,Kyeong Seok Lee,Ivan H. El-Sayed,Yuqing Deng,Matt Law,Lori E. Greene,Aleksandra Radenovic,Tevye Kuykendall,Jan Liphardt +25 more
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Carbon-Based Nanomaterials for Biomedical Applications: A Recent Study.
TL;DR: This review summarizes the most recent studies in developing of CBNs for various biomedical applications including bio-sensing, drug delivery and cancer therapy.
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