Journal ArticleDOI
New attachment following surgical treatment of human periodontal disease.
TLDR
The hypothesis that new connective tissue attachment may form on a previously periodontitis involved root surface provided cells originating from the periodontal ligament are enabled to repopulate the root surface during healing is tested and the concept that theperiodontitis affected root surface is a major preventive factor for new attachment is invalid.Abstract:
The present experiment was undertaken to test the hypothesis that new connective tissue attachment may form on a previously periodontitis involved root surface provided cells originating from the periodontal ligament are enabled to repopulate the root surface during healing. A mandibular incisor with advanced periodontal disease of long standing (the distance between the cemento-enamel junction and the alveolar bone crest was 9 mm) was subjected to periodontal surgery using a technique which during healing prevented the dentogingival epithelium and the gingival connective tissue from reaching contact with the curetted root surface. Preference was hereby given to the periodontal ligament cells to repopulate the previously diseased root surface. After 3 months of healing a block biopsy containing the incisor and surrounding tissue was sampled. The histological analysis revealed that new cementum with inserting principal fibers had formed on the previously diseased root surface. This new attachment extended in coronal direction to a level 5 mm coronal to the alveolar bone crest. This finding suggests that new attachment can be achieved by cells originating from the periodontal ligament and demonstrates that the concept that the periodontitis affected root surface is a major preventive factor for new attachment is invalid.read more
Citations
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Journal ArticleDOI
On the causes of persistent apical periodontitis: a review.
TL;DR: This article provides a comprehensive overview of the causative factors of non-resolving periapical lesions that are seen as asymptomatic radiolucencies post-treatment.
Journal ArticleDOI
New attachment formation in the human periodontium by guided tissue regeneration. Case reports.
TL;DR: The result of healing disclosed that in all teeth treated, substantial amounts of new attachment had formed, suggesting that predictable restitution of the attachment apparatus can be accomplished by using a method of treatment which is based on the principle of guided tissue regeneration.
Journal ArticleDOI
New attachment formation as the result of controlled tissue regeneration
TL;DR: The test surfaces exhibited considerably more new attachment than the control surfaces, indicating that the placement of the membrane favoured repopulation of the wound area adjacent to the roots by cells originating from the periodontal ligament.
Journal ArticleDOI
Bone augmentation techniques.
TL;DR: The techniques for reconstruction of bony defects that are reviewed in this paper include the use of particulate bone grafts and bone graft substitutes, barrier membranes for guided bone regeneration, autogenous and allogenic block grafts, and the application of distraction osteogenesis.
Journal ArticleDOI
Periodontal regeneration in a buccal dehiscence model in monkeys after application of enamel matrix proteins.
TL;DR: Application of homogenized enamel matrix or an acidic extract of the matrix containing the hydrophobic, low molecular weight proteins, amelogenins, resulted in an almost complete regeneration of acellular cementum, firmly attached to the dentin and with collagenous fibers extending over to newly formed alveolar bone.
References
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Journal ArticleDOI
The regenerative potential of the periodontal ligament. An experimental study in the monkey.
TL;DR: In this article, the authors examined if new cementum and new attachment may form during healing of a wound prepared in such a way that preference is given to periodontal ligament cells to repopulate the wound area adjacent to a root which has been surgically deprived of its ligament and cementum layer.
Journal ArticleDOI
Healing following implantation of periodontitis affected roots into bone tissue.
TL;DR: The results indicate that in addition to apical migration of junctional epithelium and regrowth of subgingival plaque, the type of cells which repopulate the wound area may jeopardize new connective tissue attachment.
Journal ArticleDOI
Healing following implantation of periodontitis-affected roots into gingival connective tissue.
TL;DR: The results indicate that gingival connective tissue does not possess the ability to establish conditions which enable the formation of a new connectives attachment on a previously periodontitis involved root surface.
Journal ArticleDOI
Connective tissue regeneration to periodontally diseased teeth. A histological study.
TL;DR: Investigation of the biological principle of new attachment of connective tissue to periodontally diseased root surfaces utilizing the previous finding that topical application of citric acid to the affected area may stimulate periodontal regeneration demonstrates that regeneration ofperiodontal tissues to a root surface that has become denuded as a result of chronic, destructive periodontAL disease is, in fact, a biological possibility.