Non alcoholic fatty liver disease in southern Iran: a population based study.
Kamran Bagheri Lankarani,Fariborz Ghaffarpasand,Mojtaba Mahmoodi,Mehrzad Lotfi,Nima Zamiri,Sayed Taghi Heydari,Mohammad Kazem Fallahzadeh,Najmeh Maharlouei,Meisam Babaeinejad,Soheila Mehravar,Bita Geramizadeh +10 more
TLDR
NAFLD in Iranian population is associated with male gender, old age, obesity, and features of metabolic syndrome, and patients with NAFLD had significantly higher prevalence of metabolic Syndrome when compared to healthy subjects.Abstract:
Background
Population based studies on prevalence and risk factors of NAFLD in Iranian population are few. The prevalence of NAFLD and non alcoholic steatohepatitis (NASH) in Iranians varies from 2.9% to 7.1% in general population and 55.8% in patients with type 2 diabetes mellitus.read more
Citations
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Global prevalence, incidence, and outcomes of non-obese or lean non-alcoholic fatty liver disease: a systematic review and meta-analysis.
Qing Ye,Biyao Zou,Yee Hui Yeo,Yee Hui Yeo,Jie Li,Daniel Q. Huang,Yuankai Wu,Yuankai Wu,Hongli Yang,Chuanli Liu,Leslie Y. Kam,Xiang Xuan Eunice Tan,Nicholas Chien,Sam Trinh,Linda Henry,Christopher D Stave,Tetsuya Hosaka,Ramsey Cheung,Ramsey Cheung,Mindie H. Nguyen +19 more
TL;DR: The findings suggest that obesity should not be the sole criterion for NAFLD screening and that both non-obese and lean groups had substantial long-term liver and non-liver comorbidities.
Journal ArticleDOI
Nonobese Fatty Liver Disease
Donghee Kim,W. Ray Kim +1 more
TL;DR: It may be important to identify high‐risk nonobese NAFLD patients and manage their metabolic profile, as lifestyle modification to reduce visceral adiposity, including dietary changes and physical activity, remains the standard of care in patients withnonobeseNAFLD.
Journal ArticleDOI
Prevalence of obesity and overweight in adults and children in Iran; a systematic review.
Shahrzad Jafari-Adli,Zahra Jouyandeh,Mostafa Qorbani,Ahmadreza Soroush,Bagher Larijani,Shirin Hasani-Ranjbar +5 more
TL;DR: The national reported prevalence of obesity in Iran was not considerably diverse, but remarkable differences were seen in the sub national prevalence which must be noticed more in political health programs especially among women and children.
Journal ArticleDOI
The Riddle of Nonalcoholic Fatty Liver Disease: Progression From Nonalcoholic Fatty Liver to Nonalcoholic Steatohepatitis.
Mithun Sharma,Shasikala Mitnala,Ravi K. Vishnubhotla,Rathin Mukherjee,Duvvur Nageshwar Reddy,Padaki Nagaraja Rao +5 more
TL;DR: The triggers implicated in disease progression from NAFL to NASH are highlighted, specifically the triggers of genes, dietary factors, innate immunity, cytokines and gut microbiome.
Journal ArticleDOI
Prevalence of Nonalcoholic Fatty Liver Disease and Economy
TL;DR: It is suggested that countries with higher economic status tend to present a higher prevalence of NAFLD, and male prevalence and rural prevalence individually were correlated with economic status.
References
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Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity
Jeffrey D. Browning,Lidia S. Szczepaniak,Robert L. Dobbins,Pamela Nuremberg,Jay D. Horton,Jonathan Cohen,Scott M. Grundy,Helen H. Hobbs +7 more
TL;DR: The prevalence of hepatic steatosis was greater in men than women among whites, but not in blacks or Hispanics, and significant ethnic and sex differences in the prevalence may have a profound impact on susceptibility to Steatosis‐related liver disease.
Journal ArticleDOI
Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults.
TL;DR: Aliment Pharmacol Ther 2011; 34: 274–285
Journal ArticleDOI
The NAFLD fibrosis score: A noninvasive system that identifies liver fibrosis in patients with NAFLD
Paul Angulo,Jason M. Hui,Giulio Marchesini,Ellisabetta Bugianesi,Jacob George,Geoffrey C. Farrell,Felicity Enders,Sushma Saksena,Alastair D. Burt,John P. Bida,Keith D. Lindor,Schuyler O. Sanderson,Marco Lenzi,Leon A. Adams,James G. Kench,Terry M. Therneau,Christopher P. Day +16 more
TL;DR: A simple scoring system accurately separates patients with nonalcoholic fatty liver disease with and without advanced fibrosis, rendering liver biopsy for identification ofAdvanced fibrosis unnecessary in a substantial proportion of patients.
Journal ArticleDOI
Nonalcoholic steatohepatitis: Summary of an AASLD Single Topic Conference
Brent A. Neuschwander-Tetri,Brent A. Neuschwander-Tetri,Stephen H. Caldwell,Stephen H. Caldwell +3 more
TL;DR: The research agenda for the future includes establishing the role of insulin resistance and abnormal lipoprotein metabolism in NASH, determining the pathogenesis of cellular injury, defining predisposing genetic abnormalities, identifying better noninvasive predictors of disease, and defining effective therapy.
Journal ArticleDOI
Prevalence of and risk factors for nonalcoholic fatty liver disease: The Dionysos nutrition and liver study†‡
Giorgio Bedogni,L. Miglioli,Flora Masutti,Claudio Tiribelli,Giulio Marchesini,Stefano Bellentani +5 more
TL;DR: NAFLD is highly prevalent in the general population, is not associated with SLD, but is associated with many features of the metabolic syndrome.