Journal ArticleDOI
Polyurethane Elastomer Biostability
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TLDR
A new polycarbonate polyurethane has superior biostability in early in vivo qualification tests compared to the polyetherpolyurethanes, including no evidence of hydrolysis, ESC or MIO.Abstract:
Polyurethanes have unique mechanical and biologic properties that make them ideal for many implantable devices. They are subject to some in vivo degradation mechanisms, however. Polyester polyurethanes are subject to hydrolytic degradation and are no longer used in long-term implanted devices. Polyether polyurethanes, while hydrolytically stable, are subject to oxidative degradation in several forms, including environmental stress cracking and metal ion oxidation. Mineralization is also known to occur. A new polycarbonate polyurethane has superior biostability in early in vivo qualification tests compared to the polyether polyurethanes, including no evidence of hydrolysis, ESC or MIO.read more
Citations
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Journal ArticleDOI
Elastomeric biomaterials for tissue engineering
TL;DR: This article provides a comprehensive review on the elastomeric biomaterials used in tissue engineering, with emphasis on the most important candidates to date.
Journal ArticleDOI
Understanding the biodegradation of polyurethanes: From classical implants to tissue engineering materials
TL;DR: The current review will briefly survey the literature, which initially identified the problem of PU degradation in vivo and the subsequent studies that have led to the field's further understanding of the biological processes mediating the breakdown.
Journal ArticleDOI
Biodegradable Polyurethanes: Synthesis and Applications in Regenerative Medicine
TL;DR: This review article summarizes recent advances made in the synthesis of biodegradable PURs and the application of these materials as scaffolds for regenerative medicine.
Journal ArticleDOI
Degradability of Polymers for Implantable Biomedical Devices
Suping Lyu,Darrel Untereker +1 more
TL;DR: Physical degradation such interfacial delamination in composites is discussed and hydrolysis and oxidation are discussed in detail in the context of the environmental factors that impact the utility of various polymers for medical device applications.
Journal ArticleDOI
The Mechanical Behavior of Vascular Grafts: A Review
Henryk J. Salacinski,Sean Goldner,A Giudiceandrea,George Hamilton,Alexander M. Seifalian,Alan Edwards,Robert J. Carson +6 more
TL;DR: How mechanical properties including compliance mismatch, diameter mismatch, Young’s modulus and impedance phase angle affect graft failure due to intimal hyperplasia is discussed.
References
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Book
CRC Handbook of Chemistry and Physics
TL;DR: CRC handbook of chemistry and physics, CRC Handbook of Chemistry and Physics, CRC handbook as discussed by the authors, CRC Handbook for Chemistry and Physiology, CRC Handbook for Physics,
Book
Textbook of Medical Physiology
Arthur C. Guyton,John E. Hall +1 more
TL;DR: Textbook of medical physiology , Textbook ofmedical physiology , کتابخانه دیجیتال جندی شاپور اهواز
Journal ArticleDOI
Textbook of Medical Physiology
TL;DR: Textbook of medical physiology, Textbook of Medical Physiology, this paper, textbook of medicine, textbooks of medical science, text book of medical literature, textbook medical physiology.
Journal ArticleDOI
Macrophages and polymorphonuclear neutrophils in lung defense and injury
Yves Sibille,Herbert Y. Reynolds +1 more
TL;DR: Alveolar macrophages are part of the regulatory mechanisms of PMN mobility and adherence that appears to be crucial in the initiation of some inflammatory reactions, and this supports a central role for alveolarmacrophages in the regulation of PMn traffic in the lungs.
Journal ArticleDOI
Inflammatory response to implants.
TL;DR: An hypothesis on the role of complement activation and complement-mediated cellular adhesion to implant surfaces has been presented and macrophage adhesion and subsequent activation leading to cell-mediator and cell-cell communication is described.