Preparation of PLGA-chitosan based nanocarriers for enhancing antibacterial effect of ciprofloxacin in root canal infection.
TLDR
F3 had proven to exhibit potential antibacterial and antibiofilm activity in a controlled release pattern consequently, they can be used as an intra-canal medication.Abstract:
The aim of this study is to prepare and evaluate the antibacterial and antibiofilm activity of ciprofloxacin (CIP) loaded PLGA nanoparticles (F2) and CIP-PLGA nanoparticles coated with chitosan (F3...read more
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Chitosan biomaterials application in dentistry.
Elaheh Fakhri,Hosein Eslami,Parham Maroufi,Farzaneh Pakdel,Sepehr Taghizadeh,Khudaverdi Ganbarov,Mehdi Yousefi,Asghar Tanomand,Bahman Yousefi,Shahla Mahmoudi,Hossein Samadi Kafil +10 more
TL;DR: The crucial role of chitosan in production of bio-dental materials is discussed and its current profitable utilizations in oral drug delivery system, bone tissue engineering for treatment of periodontitis and dentin-pulp regeneration are accentuated.
Journal ArticleDOI
Drug Delivery (Nano)Platforms for Oral and Dental Applications: Tissue Regeneration, Infection Control, and Cancer Management
Pooyan Makvandi,Uros Josic,Masoud Delfi,Filippo Pinelli,Vahid Jahed,Emine Kaya,Milad Ashrafizadeh,Atefeh Zarepour,Filippo Rossi,Ali Zarrabi,Tarun Agarwal,Ehsan Nazarzadeh Zare,Matineh Ghomi,Tapas K. Maiti,Lorenzo Breschi,Franklin R. Tay +15 more
TL;DR: An overview of newly-developed nanocarriers and their potential applications and limitations in various fields of dentistry and oral medicine can be found in this article, where the authors discuss their potential application and limitations.
Journal ArticleDOI
Chitosan-Coated PLGA Nanoparticles for Enhanced Ocular Anti-Inflammatory Efficacy of Atorvastatin Calcium.
TL;DR: AT-PLGA-CS-NP thermosensitive gels proved to be successful ocular anti-inflammatory drug delivery systems in rabbits by counting the polymorphonuclear leukocytes (PMNs) and protein migrated in tears.
Journal ArticleDOI
Synthesis and characterization of injectable self-healing hydrogels based on oxidized alginate-hybrid-hydroxyapatite nanoparticles and carboxymethyl chitosan.
Lei Ma,Wen Su,Yaqin Ran,Xiaomin Ma,Zeng Yi,Guangcan Chen,Xiangyu Chen,Zhiwen Deng,Qiulan Tong,Xiaoliang Wang,Xudong Li +10 more
TL;DR: The injectable hydrogels with self-healing and tunable gelling properties were ingeniously prepared with functionalized alginate-mediated HA hybrid nanoparticles, and these hydrogel are promising for applications in bone tissue engineering.
Journal ArticleDOI
In Vitro Drug Release, Permeability, and Structural Test of Ciprofloxacin-Loaded Nanofibers
Luca Éva Uhljar,Sheng Yuan Kan,Norbert Radacsi,Vasileios Koutsos,Piroska Szabó-Révész,Rita Ambrus +5 more
TL;DR: In this article, Ciprofloxacin-loaded poly(vinyl pyrrolidone) (PVP) nanofibers can be considered as fast-dissolving formulations with improved physicochemical properties.
References
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