Journal ArticleDOI
Reversible cerebral vasoconstriction syndrome
TLDR
Reversible cerebral vasoconstriction syndrome is characterised by severe headaches with or without seizures and focal neurological deficits, and constriction of cerebral arteries which resolves spontaneously in 1–3 months, with no definite effect on the haemorrhagic and ischaemic complications.Abstract:
Reversible cerebral vasoconstriction syndrome is characterised by severe headaches with or without seizures and focal neurological deficits, and constriction of cerebral arteries which resolves spontaneously in 1-3 months. It affects females slightly more than males, and mean age of onset is around 45 years. Approximately 60% of cases are secondary, mainly postpartum and after exposure to vasoactive substances. The major complications are localised cortical subarachnoid haemorrhage (22%) and parenchymal ischaemic or haemorrhagic strokes (7%) which may leave permanent sequelae. Diagnosis requires the demonstration of the "string of beads" appearance of cerebral arteries on angiography, with complete or almost complete resolution on repeat angiography 12 weeks after onset. Nimodipine seems to reduce thunderclap headaches within 48 h but has no definite effect on the haemorrhagic and ischaemic complications.read more
Citations
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Journal ArticleDOI
Reversible cerebral vasoconstriction syndrome
TL;DR: Recurrent thunderclap headaches, seizures, strokes, and non-aneurysmal subarachnoid haemorrhage can all reveal reversible cerebral vasoconstriction syndrome, characterised by severe headaches, and segmental constriction of cerebral arteries that resolves within 3 months.
Journal ArticleDOI
Cortical superficial siderosis: detection and clinical significance in cerebral amyloid angiopathy and related conditions.
Andreas Charidimou,Andreas Charidimou,Jennifer Linn,Meike W. Vernooij,Christian Opherk,Saloua Akoudad,Jean-Claude Baron,Steven M. Greenberg,Hans Rolf Jäger,David J. Werring +9 more
TL;DR: Recent developments in neuroimaging and detection, aetiology, prevalence, pathophysiology and clinical significance of cortical superficial siderosis are focused on, with a particular emphasis on cerebral amyloid angiopathy.
Journal ArticleDOI
The posterior reversible encephalopathy syndrome: what's certain, what's new?
TL;DR: Seizures do not normally progress to chronic epilepsy so antiepileptic drugs should be discontinued after about 3 months, and recovery within a few days, while the MRI abnormalities resolve much more slowly.
Journal ArticleDOI
Adult primary central nervous system vasculitis
TL;DR: The differential diagnosis includes reversible cerebral vasoconstriction syndromes and secondary cerebral vasculitis, which generally consist of headache, altered cognition, focal weakness, or stroke.
Journal ArticleDOI
Imaging Spectrum of CNS Vasculitis
Ahmed Abdel Khalek Abdel Razek,Hortensia Alvarez,Stephen Bagg,Sherif Refaat,Mauricio Castillo +4 more
TL;DR: Correlation of imaging findings with clinical presentation and laboratory test results helps establish the diagnosis of CNS vasculitis.
References
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Journal ArticleDOI
A reversible posterior leukoencephalopathy syndrome
Judy Hinchey,Claudia Chaves,B A Appignani,Joan Breen,Linda Pao,Annabel Wang,Michael S. Pessin,Catherine Lamy,Jean-Louis Mas,Louis R. Caplan +9 more
TL;DR: Reversible, predominantly posterior leukoencephalopathy may develop in patients who have renal insufficiency or hypertension or who are immunosuppressed and the findings on neuroimaging are characteristic of subcortical edema without infarction.
Journal ArticleDOI
A Report on the Journal 2004
TL;DR: From this issue Cephalalgia will become a monthly journal and has a strong throughput of excellent work and rather than raise the rejection rate, and somewhat arbitrarily dismiss work that readers might be very interested in seeing, it is timely to increase to 12 issues a year.
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Posterior reversible encephalopathy syndrome, part 1: fundamental imaging and clinical features.
TL;DR: Posterior reversible encephalopathy syndrome is a neurotoxic state coupled with a unique CT or MR imaging appearance, recognized in the setting of a number of complex conditions.
Journal ArticleDOI
The clinical and radiological spectrum of reversible cerebral vasoconstriction syndrome. A prospective series of 67 patients.
TL;DR: The data suggest that RCVS is more frequent than previously thought, is more often secondary particularly to vasoactive substances, and should be considered in patients with recurrent thunderclap headaches, cSAH or cryptogenic strokes with severe headaches.
Journal ArticleDOI
Posterior reversible encephalopathy syndrome, part 2: controversies surrounding pathophysiology of vasogenic edema.
TL;DR: Systemic features in PRES appear to render strong support for the older theory of vasoconstriction coupled with hypoperfusion as the mechanism, including supporting evidence and current available imaging/clinical data related to the conditions that develop PRES.