REVIGO Summarizes and Visualizes Long Lists of Gene Ontology Terms
TLDR
REVIGO is a Web server that summarizes long, unintelligible lists of GO terms by finding a representative subset of the terms using a simple clustering algorithm that relies on semantic similarity measures.Abstract:
Outcomes of high-throughput biological experiments are typically interpreted by statistical testing for enriched gene functional categories defined by the Gene Ontology (GO). The resulting lists of GO terms may be large and highly redundant, and thus difficult to interpret.
REVIGO is a Web server that summarizes long, unintelligible lists of GO terms by finding a representative subset of the terms using a simple clustering algorithm that relies on semantic similarity measures. Furthermore, REVIGO visualizes this non-redundant GO term set in multiple ways to assist in interpretation: multidimensional scaling and graph-based visualizations accurately render the subdivisions and the semantic relationships in the data, while treemaps and tag clouds are also offered as alternative views. REVIGO is freely available at http://revigo.irb.hr/.read more
Citations
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g:Profiler: a web server for functional enrichment analysis and conversions of gene lists (2019 update).
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N6-methyladenosine Modulates Messenger RNA Translation Efficiency
Xiao Wang,Xiao Wang,Boxuan Simen Zhao,Boxuan Simen Zhao,Ian A Roundtree,Ian A Roundtree,Zhike Lu,Zhike Lu,Dali Han,Dali Han,Honghui Ma,Honghui Ma,Xiaocheng Weng,Xiaocheng Weng,Kai Chen,Kai Chen,Hailing Shi,Hailing Shi,Chuan He,Chuan He +19 more
TL;DR: In a unified mechanism of m(6)A-based regulation in the cytoplasm, YTHDF2-mediated degradation controls the lifetime of target transcripts, whereasYTHDF1-mediated translation promotion increases translation efficiency, ensuring effective protein production from dynamic transcripts that are marked by m( 6)A.
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A chromosome-based draft sequence of the hexaploid bread wheat (Triticum aestivum) genome
Klaus F. X. Mayer,Jane Rogers,Jaroslav Doležel,Curtis J. Pozniak,Kellye Eversole,Catherine Feuillet,Bikram S. Gill,Bernd Friebe,Adam J. Lukaszewski,Pierre Sourdille,Takashi R. Endo,M. Kubaláková,Jarmila Číhalíková,Zdeňka Dubská,Jan Vrána,Romana Šperková,Hana Šimková,Melanie Febrer,Leah Clissold,Kirsten McLay,Kuldeep Singh,Parveen Chhuneja,Nagendra K. Singh,Jitendra P. Khurana,Eduard Akhunov,Frédéric Choulet,Adriana Alberti,Valérie Barbe,Patrick Wincker,Hiroyuki Kanamori,Fuminori Kobayashi,Takeshi Itoh,Takashi Matsumoto,Hiroaki Sakai,Tsuyoshi Tanaka,Jianzhong Wu,Yasunari Ogihara,Hirokazu Handa,P. Ron Maclachlan,Andrew G. Sharpe,Darrin Klassen,David Edwards,Jacqueline Batley,Odd-Arne Olsen,Simen Rød Sandve,Sigbjørn Lien,Burkhard Steuernagel,Brande B. H. Wulff,Mario Caccamo,Sarah Ayling,Ricardo H. Ramirez-Gonzalez,Bernardo J. Clavijo,Jonathan M. Wright,Matthias Pfeifer,Manuel Spannagl,Mihaela Martis,Martin Mascher,Jarrod Chapman,Jesse Poland,Uwe Scholz,Kerrie Barry,Robbie Waugh,Daniel S. Rokhsar,Gary J. Muehlbauer,Nils Stein,Heidrun Gundlach,Matthias Zytnicki,Véronique Jamilloux,Hadi Quesneville,Thomas Wicker,Primetta Faccioli,Moreno Colaiacovo,Antonio Michele Stanca,Hikmet Budak,Luigi Cattivelli,Natasha Glover,Lise Pingault,Etienne Paux,Sapna Sharma,Rudi Appels,Matthew I. Bellgard,Brett Chapman,Thomas Nussbaumer,Kai Christian Bader,Hélène Rimbert,Shichen Wang,Ron Knox,Andrzej Kilian,Michael Alaux,Françoise Alfama,Loïc Couderc,Nicolas Guilhot,Claire Viseux,Mikaël Loaec,Beat Keller,Sébastien Praud +95 more
TL;DR: Insight into the genome biology of a polyploid crop provide a springboard for faster gene isolation, rapid genetic marker development, and precise breeding to meet the needs of increasing food demand worldwide.
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A chromosome conformation capture ordered sequence of the barley genome
Martin Mascher,Heidrun Gundlach,Axel Himmelbach,Sebastian Beier,Sven Twardziok,Thomas Wicker,Volodymyr Radchuk,Christoph Dockter,Pete E. Hedley,Joanne Russell,Micha Bayer,Luke Ramsay,Hui Liu,Georg Haberer,Xiao-Qi Zhang,Qisen Zhang,Roberto A. Barrero,Lin Li,Stefan Taudien,Marco Groth,Marius Felder,Alex Hastie,Hana Šimková,Helena Staňková,Jan Vrána,Saki Chan,María Muñoz-Amatriaín,Rachid Ounit,Steve Wanamaker,Dan Bolser,Christian Colmsee,Thomas Schmutzer,Lala Aliyeva-Schnorr,Stefano Grasso,Jaakko Tanskanen,Anna Chailyan,Dharanya Sampath,Darren Heavens,Leah Clissold,Sujie Cao,Brett Chapman,Fei Dai,Yong Han,Hua Li,Xuan Li,Chongyun Lin,John K. McCooke,Cong Tan,Penghao Wang,Songbo Wang,Shuya Yin,Gaofeng Zhou,Jesse Poland,Matthew I. Bellgard,Ljudmilla Borisjuk,Andreas Houben,Jaroslav Doležel,Sarah Ayling,Stefano Lonardi,Paul J. Kersey,Peter Langridge,Gary J. Muehlbauer,Matthew D. Clark,Matthew D. Clark,Mario Caccamo,Mario Caccamo,Alan H. Schulman,Klaus F. X. Mayer,Matthias Platzer,Timothy J. Close,Uwe Scholz,Mats Hansson,Guoping Zhang,Ilka Braumann,Manuel Spannagl,Chengdao Li,Chengdao Li,Chengdao Li,Robbie Waugh,Robbie Waugh,Nils Stein,Nils Stein +81 more
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