Selective review of cognitive aging
TLDR
Questions related to age, how many distinct influences are contributing to the relations between age and cognitive functioning, do the differences between people increase with advancing age, and what is responsible for the discrepancies between cross-sectional and longitudinal age comparisons of cognitive functioning are reviewed.Abstract:
Research concerned with relations between adult age and cognitive functioning is briefly reviewed. The coverage is necessarily selective, and is organized in terms of five major questions. These are what abilities are related to age, how many distinct influences are contributing to the relations between age and cognitive functioning, do the differences between people increase with advancing age, what is responsible for the discrepancies between cross-sectional and longitudinal age comparisons of cognitive functioning, and what methods can be used to identify causes of age-related influences on cognition. Although definitive answers are not yet possible, quite a bit of information relevant to the questions is now available. Moreover, the existing information has implications for the design, analysis, and interpretation of cognitive and neuropsychological research concerned with aging.read more
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Journal ArticleDOI
Normal Cognitive Aging
TL;DR: The neurocognitive changes observed in normal aging are described, followed by a description of the structural and functional alterations seen in aging brains.
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Safety of Transcranial Direct Current Stimulation: Evidence Based Update 2016.
Marom Bikson,Pnina Grossman,Chris Thomas,Adantchede L. Zannou,Jimmy Jiang,Tatheer Adnan,Antonios P. Mourdoukoutas,Greg Kronberg,Dennis Q. Truong,Paulo S. Boggio,Andre R. Brunoni,Leigh Charvet,Felipe Fregni,Brita Fritsch,Bernadette T. Gillick,Roy H. Hamilton,Benjamin M. Hampstead,Ryan Jankord,Adam Kirton,Helena Knotkova,David Liebetanz,Anli Liu,Colleen Loo,Michael A. Nitsche,Janine Reis,Janine Reis,Jessica D. Richardson,Alexander Rotenberg,Peter E. Turkeltaub,Adam J. Woods +29 more
TL;DR: Evidence from relevant animal models indicates that brain injury by Direct Current Stimulation (DCS) occurs at predicted brain current densities that are over an order of magnitude above those produced by conventional tDCS.
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The Impact of Age on Cognition
TL;DR: The most important changes in cognition with normal aging are declines in performance on cognitive tasks that require one to quickly process or transform information to make a decision, including measures of speed of processing, working memory and executive cognitive function.
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The Alzheimer's disease mitochondrial cascade hypothesis: progress and perspectives.
TL;DR: The mitochondrial cascade hypothesis unequivocally states in sporadic, late-onset AD, mitochondrial function affects amyloid precursor protein (APP) expression, APP processing, or beta amyloids (Aβ) accumulation and argues if an amyloidal cascade truly exists, mitochondria function triggers it.
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Association of Age-Related Hearing Loss With Cognitive Function, Cognitive Impairment, and Dementia: A Systematic Review and Meta-analysis.
David G. Loughrey,Michelle E. Kelly,Michelle E. Kelly,George A. Kelley,Sabina Brennan,Brian A. Lawlor,Brian A. Lawlor +6 more
TL;DR: Age-related hearing loss is a possible biomarker and modifiable risk factor for cognitive decline, cognitive impairment, and dementia and a small but significant association was found within all domains of cognitive function.
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