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The antimicrobial effects of extracts of Azadirachta indica (Neem) and Salvadora persica (Arak) chewing sticks.

Khalid Almas
- 01 Jan 1999 - 
- Vol. 10, Iss: 1, pp 23-26
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TLDR
Comparing the effectiveness of antimicrobial activity of Neem and Arak chewing stick's aqueous extracts at various concentrations suggested that both chewing stick extracts are effective at 50% concentration on strept mutans and Strept faecalis.
Abstract
Chewing sticks (Miswak) is most commonly used int he Middle East and Indian Subcontinent Salvadora persica (Arak) and Azadirachta indica (Neem) are commonly used as oral hygiene tools in different parts of the world, Several studies have demonstrated the anti-plaque anticarious and antibacterial effect of these sticks. The aim of this study was to compare the effectiveness of antimicrobial activity of Neem and Arak chewing stick's aqueous extracts at various concentrations. The microbial inhibition was measured using blood agar and ditch plate method up to 48 hous. The pH of Neem extract was 6.1 and of Arak was 4.9 Data suggested that both chewing stick extracts are effective at 50% concentration on strept mutans and Strept faecalis. Arak extract was more effective at lower concentrations for Strept faecalis. The effect may be due to the difference of their chemical composition and variability in their PH. Further research is needed to extrapolate other plants used for oral hygiene. Chewing sticks are recommended as oral hygiene tools for health promotion in developing countries.

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Citations
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Anti-cariogenic effects of polyphenols from plant stimulant beverages (cocoa, coffee, tea).

TL;DR: The anti-cariogenic effects against alpha-haemolytic streptococci showed by polyphenols from cocoa, coffee, and tea suggest further studies to a possible application of these beverages in the prevention of pathogenesis of dental caries.
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Benzyl isothiocyanate, a major component from the roots of Salvadora persica is highly active against Gram-negative bacteria.

TL;DR: Root extracts as well as commercial synthetic benzyl isothiocyanate exhibited rapid and strong bactericidal effect against oral pathogens involved in periodontal disease as wellAs against other Gram-negative bacteria, while Gram-positive bacteria mainly displayed growth inhibition or remained unaffected.
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A review on miswak (Salvadora persica) and its effect on various aspects of oral health.

TL;DR: The history and chemical composition of S. persica miswak and its influence on oral health, including the advantages and disadvantages of its use are discussed.
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Azadirachta indica (neem): a plant of multiple biological and pharmacological activities

TL;DR: How a developing country like Nigeria can harness the numerous opportunities presented by the multi-biological and multi-pharmacological nature of A. indica to solve some of her myriad problems, including those in the agricultural, health and economic sectors is reviewed.
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In Vitro Antimicrobial Activity of Salvadora persica L. Extracts Against Some Isolated Oral Pathogens in Iraq

TL;DR: According to both antimicrobial assays the aqueous extract inhibited all isolated microorganisms, especially the Streptococcus species, and was more efficient than the methanol extract, which was resisted by Lacto.
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